Dietary sodium and health: more than just blood pressure
Sodium is essential for cellular homeostasis and physiological function. Excess dietary sodium has been linked to elevations in blood pressure (BP). Salt sensitivity of BP varies widely, but certain subgroups tend to be more salt sensitive. The mechanisms underlying sodium-induced increases in BP ar...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2015-03, Vol.65 (10), p.1042-1050 |
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| container_title | Journal of the American College of Cardiology |
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| creator | Farquhar, William B Edwards, David G Jurkovitz, Claudine T Weintraub, William S |
| description | Sodium is essential for cellular homeostasis and physiological function. Excess dietary sodium has been linked to elevations in blood pressure (BP). Salt sensitivity of BP varies widely, but certain subgroups tend to be more salt sensitive. The mechanisms underlying sodium-induced increases in BP are not completely understood but may involve alterations in renal function, fluid volume, fluid-regulatory hormones, the vasculature, cardiac function, and the autonomic nervous system. Recent pre-clinical and clinical data support that even in the absence of an increase in BP, excess dietary sodium can adversely affect target organs, including the blood vessels, heart, kidneys, and brain. In this review, the investigators review these issues and the epidemiological research relating dietary sodium to BP and cardiovascular health outcomes, addressing recent controversies. They also provide information and strategies for reducing dietary sodium. |
| doi_str_mv | 10.1016/j.jacc.2014.12.039 |
| format | Article |
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Excess dietary sodium has been linked to elevations in blood pressure (BP). Salt sensitivity of BP varies widely, but certain subgroups tend to be more salt sensitive. The mechanisms underlying sodium-induced increases in BP are not completely understood but may involve alterations in renal function, fluid volume, fluid-regulatory hormones, the vasculature, cardiac function, and the autonomic nervous system. Recent pre-clinical and clinical data support that even in the absence of an increase in BP, excess dietary sodium can adversely affect target organs, including the blood vessels, heart, kidneys, and brain. In this review, the investigators review these issues and the epidemiological research relating dietary sodium to BP and cardiovascular health outcomes, addressing recent controversies. They also provide information and strategies for reducing dietary sodium.</description><subject>African Americans</subject><subject>Animals</subject><subject>Autonomic Nervous System - physiology</subject><subject>Blood Pressure - drug effects</subject><subject>Blood Pressure - physiology</subject><subject>Cardiac Output - physiology</subject><subject>Health Behavior</subject><subject>Humans</subject><subject>Hypertension - ethnology</subject><subject>Sodium, Dietary - pharmacology</subject><subject>Vascular Resistance - physiology</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEtLxDAUhYMoOo7-AReSpZvWPCYvF4KMTxhwo-uSNDe2pW3GphX89xYcRReHu7iH7xwOQmeU5JRQednkjS3LnBG6yinLCTd7aEGF0BkXRu2jBVFcZJQYdYSOU2oIIVJTc4iOmFBSGsEWSN_WMNrhE6fo66nDtve4AtuO1RXu4gB4rGyPmymN2LUxerwdIKVpgBN0EGyb4HR3l-j1_u5l_Zhtnh-e1jebbMukHDPtmeIqGA2cBaFLG2QIwfGVd6WxoIULkqwgAHPCm8Cc1kRBaWc5y7nnS3T9zd1OrgNfQj8Oti22Q93NtYto6-L_p6-r4i1-FIIYzY2cARc7wBDfJ0hj0dWphLa1PcQpFVSquaHmzMzW879ZvyE_c_EvgytwFQ</recordid><startdate>20150317</startdate><enddate>20150317</enddate><creator>Farquhar, William B</creator><creator>Edwards, David G</creator><creator>Jurkovitz, Claudine T</creator><creator>Weintraub, William S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150317</creationdate><title>Dietary sodium and health: more than just blood pressure</title><author>Farquhar, William B ; Edwards, David G ; Jurkovitz, Claudine T ; Weintraub, William S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p266t-8d2737f98e32f58caf6fffb34dbc9ae85bf604efe2b5d9f2b8807eca7ecba33d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>African Americans</topic><topic>Animals</topic><topic>Autonomic Nervous System - physiology</topic><topic>Blood Pressure - drug effects</topic><topic>Blood Pressure - physiology</topic><topic>Cardiac Output - physiology</topic><topic>Health Behavior</topic><topic>Humans</topic><topic>Hypertension - ethnology</topic><topic>Sodium, Dietary - pharmacology</topic><topic>Vascular Resistance - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Farquhar, William B</creatorcontrib><creatorcontrib>Edwards, David G</creatorcontrib><creatorcontrib>Jurkovitz, Claudine T</creatorcontrib><creatorcontrib>Weintraub, William S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Farquhar, William B</au><au>Edwards, David G</au><au>Jurkovitz, Claudine T</au><au>Weintraub, William S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary sodium and health: more than just blood pressure</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2015-03-17</date><risdate>2015</risdate><volume>65</volume><issue>10</issue><spage>1042</spage><epage>1050</epage><pages>1042-1050</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>Sodium is essential for cellular homeostasis and physiological function. 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| ispartof | Journal of the American College of Cardiology, 2015-03, Vol.65 (10), p.1042-1050 |
| issn | 0735-1097 1558-3597 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | African Americans Animals Autonomic Nervous System - physiology Blood Pressure - drug effects Blood Pressure - physiology Cardiac Output - physiology Health Behavior Humans Hypertension - ethnology Sodium, Dietary - pharmacology Vascular Resistance - physiology |
| title | Dietary sodium and health: more than just blood pressure |
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