Acute flaccid myelitis: A clinical review of US cases 2012-2015
This review highlights clinical features of the increasing cases of acute flaccid paralysis associated with anterior myelitis noted in the United States from 2012 to 2015. Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesions on imaging or evidence of spin...
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| Veröffentlicht in: | Annals of neurology 2016-09, Vol.80 (3), p.326-338 |
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| container_title | Annals of neurology |
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| creator | Messacar, Kevin Schreiner, Teri L. Van Haren, Keith Yang, Michele Glaser, Carol A. Tyler, Kenneth L. Dominguez, Samuel R. |
| description | This review highlights clinical features of the increasing cases of acute flaccid paralysis associated with anterior myelitis noted in the United States from 2012 to 2015. Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesions on imaging or evidence of spinal cord motor neuron injury on electrodiagnostic testing. Although some individuals demonstrated improvement in motor weakness and functional deficits, most have residual weakness a year or more after onset. Epidemiological evidence and biological plausibility support an association between enterovirus D68 and the recent increase in acute flaccid myelitis cases in the United States. Ann Neurol 2016;80:326–338 |
| doi_str_mv | 10.1002/ana.24730 |
| format | Article |
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Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesions on imaging or evidence of spinal cord motor neuron injury on electrodiagnostic testing. Although some individuals demonstrated improvement in motor weakness and functional deficits, most have residual weakness a year or more after onset. Epidemiological evidence and biological plausibility support an association between enterovirus D68 and the recent increase in acute flaccid myelitis cases in the United States. 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| ispartof | Annals of neurology, 2016-09, Vol.80 (3), p.326-338 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Child Enterovirus Enterovirus D, Human - pathogenicity Enterovirus Infections - complications Enteroviruses Epidemiology Humans Motor Neurons - pathology Myelitis Myelitis - diagnostic imaging Myelitis - etiology Myelitis - physiopathology Paralysis Paralysis - diagnostic imaging Paralysis - etiology Paralysis - physiopathology Spinal cord Spinal cord injuries Substantia grisea United States Vaccines |
| title | Acute flaccid myelitis: A clinical review of US cases 2012-2015 |
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