Differences in Patient Characteristics and Midterm Outcome Between Asian and European Patients Treated with Radiofrequency Ablation for Hepatocellular Carcinoma

Purpose The aim of this study was to compare patient characteristics and midterm outcomes after RFA for unresectable Hepatocellular carcinoma (HCC) in Asian and European cohorts. Materials and Methods The study was based on retrospective analysis of 279 patients (mean 64.8 ± 12.1 years; 208 males) t...

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Veröffentlicht in:	Cardiovascular and interventional radiology 2016-12, Vol.39 (12), p.1708-1715
Hauptverfasser:	Burgmans, Mark Christiaan, Too, Chow Wei, Fiocco, Marta, Kerbert, Annarein J. C., Lo, Richard Hoau Gong, Schaapman, Jelte J., van Erkel, Arian R., Coenraad, Minneke J., Tan, Bien Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	ABLATION Age Factors Aged Asian Continental Ancestry Group - statistics & numerical data Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - surgery Cardiology Catheter Ablation - methods Causality Clinical Investigation Comorbidity COMPARATIVE EVALUATIONS DEATH ETIOLOGY European Continental Ancestry Group - statistics & numerical data Female Follow-Up Studies HAZARDS HEPATITIS Hepatitis B - epidemiology Hepatitis B virus HEPATOMAS Humans Imaging Incidence Liver Cirrhosis, Alcoholic - epidemiology Liver Neoplasms - epidemiology Liver Neoplasms - surgery Male Medicine Medicine & Public Health Middle Aged Neoplasm Recurrence, Local - epidemiology NETHERLANDS Nuclear Medicine PATIENTS Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOWAVE RADIATION Retrospective Studies SINGAPORE Treatment Outcome Ultrasound
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Zusammenfassung:	Purpose The aim of this study was to compare patient characteristics and midterm outcomes after RFA for unresectable Hepatocellular carcinoma (HCC) in Asian and European cohorts. Materials and Methods The study was based on retrospective analysis of 279 patients (mean 64.8 ± 12.1 years; 208 males) treated with RFA for de novo HCC in tertiary referral centers in Singapore and the Netherlands, with median follow-up of 28.2 months (quartiles: 13.1–40.5 months). Cumulative incidence of recurrence and death were analyzed using a competing risk model. Results Age was higher in the Asian group: 66.5 versus 60.1 years ( p
ISSN:	0174-1551 1432-086X
DOI:	10.1007/s00270-016-1462-7