Lung Metabolic Activation as an Early Biomarker of Acute Respiratory Distress Syndrome and Local Gene Expression Heterogeneity

BACKGROUND:Acute respiratory distress syndrome (ARDS) is an inflammatory condition comprising diffuse lung edema and alveolar damage. ARDS frequently results from regional injury mechanisms. However, it is unknown whether detectable inflammation precedes lung edema and opacification and whether topo...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2016-11, Vol.125 (5), p.992-1004
Hauptverfasser:	Wellman, Tyler J, de Prost, Nicolas, Tucci, Mauro, Winkler, Tilo, Baron, Rebecca M, Filipczak, Piotr, Raby, Benjamin, Chu, Jen-hwa, Harris, R Scott, Musch, Guido, dos Reis Falcao, Luiz F, Capelozzi, Vera, Venegas, Jose G, Vidal Melo, Marcos F
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation, Metabolic Animals Biomarkers - metabolism Disease Models, Animal Fluorodeoxyglucose F18 Gene Expression Lung - diagnostic imaging Lung - metabolism Positron-Emission Tomography Radiopharmaceuticals Respiratory Distress Syndrome - diagnostic imaging Respiratory Distress Syndrome - metabolism Respiratory Distress Syndrome - physiopathology Sheep
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