Isolation and Characterization of Reticuline N-Methyltransferase Involved in Biosynthesis of the Aporphine Alkaloid Magnoflorine in Opium Poppy

Benzylisoquinoline alkaloids are a large group of plant-specialized metabolites displaying an array of biological and pharmacological properties associated with numerous structural scaffolds and diverse functional group modification. N-Methylation is one of the most common tailoring reactions, yield...

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Veröffentlicht in:	The Journal of biological chemistry 2016-11, Vol.291 (45), p.23416-23427
Hauptverfasser:	Morris, Jeremy S., Facchini, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence aporphine alkaloid Aporphines - metabolism benzylisoquinoline alkaloid Benzylisoquinolines - metabolism biochemical genomics biosynthesis Biosynthetic Pathways enzyme catalysis functional genomics Gene Expression Regulation, Enzymologic Gene Expression Regulation, Plant magnoflorine Methyltransferases - chemistry Methyltransferases - genetics Methyltransferases - isolation & purification Methyltransferases - metabolism N-methyltransferase Papaver - chemistry Papaver - enzymology Papaver - genetics Papaver - metabolism Phylogeny plant biochemistry Plant Biology secondary metabolism Sequence Alignment
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