Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells

Although many breast and lung cancers overexpress human epidermal growth factor receptor-2 (HER-2), no methods currently exist for effective and early detection of HER-2-positive cancers. To address this issue, we designed and synthesized dendrimer-based novel nano-imaging agents that contain gold n...

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Veröffentlicht in:Oncotarget 2016-06, Vol.7 (24), p.36002-36013
Hauptverfasser: Otis, James B, Zong, Hong, Kotylar, Alina, Yin, Anna, Bhattacharjee, Somnath, Wang, Han, Baker, Jr, James R, Wang, Su He
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Sprache:eng
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