Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10

Previously we presented suggestive evidence from an F2 segregating population for an interaction on blood pressure (BP) between quantitative trait loci (QTL) on rat chromosomes (Chr) 2 and 10. To prove the existence of such an interaction, we developed congenic strains for Chr 2 and 10 by introgress...

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Veröffentlicht in:The Journal of clinical investigation 1998-04, Vol.101 (8), p.1591-1595
Hauptverfasser: Rapp, J P, Garrett, M R, Deng, A Y
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Sprache:eng
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