RIG-I activation induces the release of extracellular vesicles with antitumor activity

Activation of the innate immune receptor retinoic acid-inducible gene I (RIG-I) by its specific ligand 5′-triphosphate-RNA (3pRNA) triggers antitumor immunity predominantly via NK cell activation and direct apoptosis induction in tumor cells. However, how NK cells are mobilized to attack the tumor c...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Oncoimmunology 2016-10, Vol.5 (10), p.e1219827-e1219827
Hauptverfasser:	Daßler-Plenker, Juliane, Reiners, Katrin S., van den Boorn, Jasper G., Hansen, Hinrich P., Putschli, Bastian, Barnert, Sabine, Schuberth-Wagner, Christine, Schubert, Rolf, Tüting, Thomas, Hallek, Michael, Schlee, Martin, Hartmann, Gunther, Pogge von Strandmann, Elke, Coch, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	BAG6 exosomes extracellular vesicles melanoma NK cells NKp30 Original Research RIG-I
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!