Involvement of nitric oxide system in experimental muscle crush injury

Muscle crush injury is often complicated by hemodynamic shock, electrolyte disorders, and myoglobinuric renal failure. In this study, we examined the involvement of the nitric oxide (NO) system in the development of muscle damage in an experimental model of crush injury induced by exertion of standa...

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Veröffentlicht in:	The Journal of clinical investigation 1998-03, Vol.101 (6), p.1325-1333
Hauptverfasser:	Rubinstein, I, Abassi, Z, Coleman, R, Milman, F, Winaver, J, Better, O S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Flow Velocity Blotting, Western Capillaries - physiopathology Dilatation, Pathologic - physiopathology Endothelium, Vascular - enzymology Endothelium, Vascular - metabolism Enzyme Inhibitors - pharmacology Femoral Artery - physiopathology Hindlimb - injuries Hindlimb - metabolism Isoenzymes - genetics Isoenzymes - immunology Isoenzymes - metabolism Muscle, Skeletal - blood supply Muscle, Skeletal - injuries Muscle, Skeletal - metabolism NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - metabolism Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type I Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Polymerase Chain Reaction Rats Rats, Sprague-Dawley RNA, Messenger - metabolism
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