Triflumuron Effects on the Physiology and Reproduction of Rhodnius prolixus Adult Females
We evaluated the efficacy of the growth regulator triflumuron (TFM) in inducing mortality and disrupting both oviposition and egg hatching in Rhodnius prolixus adult females. TFM was administered via feeding, topically or by continuous contact with impregnated surfaces. Feeding resulted in mild biol...
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creator | Feder, Denise Gonzalez, Marcelo Salabert Azambuja, Patricia Valle, Denise Marinho, Lourena Pinheiro Oliveira, Alyne F. R. Codogno, Thaís Franco Silva, Lucas Rangel Mello, Cícero Brasileiro Genta, Fernando A. Henriques, Bianca Santos Lima, José Bento Pereira |
description | We evaluated the efficacy of the growth regulator triflumuron (TFM) in inducing mortality and disrupting both oviposition and egg hatching in Rhodnius prolixus adult females. TFM was administered via feeding, topically or by continuous contact with impregnated surfaces. Feeding resulted in mild biological effects compared with topical and impregnated surfaces. One day after treatment, the highest mortality levels were observed with topical surface and 30 days later both topical and impregnated surfaces induced higher mortalities than feeding. Oral treatment inhibited oviposition even at lower doses, and hatching of eggs deposited by treated females was similarly affected by the three delivery modes. Topical treatment of eggs deposited by nontreated females significantly reduced hatching. However, treatment per contact of eggs oviposited by untreated females did not disrupt eclosion. Additionally, oral treatment increased the number of immature oocytes per female, and topical treatment reduced the mean size of oocytes. TFM also affected carcass chitin content, diuresis, and innate immunity of treated insects. These results suggest that TFM acts as a potent growth inhibitor of R. prolixus adult females and has the potential to be used in integrated vector control programs against hematophagous triatomine species. |
doi_str_mv | 10.1155/2016/8603140 |
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R. ; Codogno, Thaís Franco ; Silva, Lucas Rangel ; Mello, Cícero Brasileiro ; Genta, Fernando A. ; Henriques, Bianca Santos ; Lima, José Bento Pereira</creator><contributor>Cabaret, Jacques</contributor><creatorcontrib>Feder, Denise ; Gonzalez, Marcelo Salabert ; Azambuja, Patricia ; Valle, Denise ; Marinho, Lourena Pinheiro ; Oliveira, Alyne F. R. ; Codogno, Thaís Franco ; Silva, Lucas Rangel ; Mello, Cícero Brasileiro ; Genta, Fernando A. ; Henriques, Bianca Santos ; Lima, José Bento Pereira ; Cabaret, Jacques</creatorcontrib><description>We evaluated the efficacy of the growth regulator triflumuron (TFM) in inducing mortality and disrupting both oviposition and egg hatching in Rhodnius prolixus adult females. TFM was administered via feeding, topically or by continuous contact with impregnated surfaces. Feeding resulted in mild biological effects compared with topical and impregnated surfaces. One day after treatment, the highest mortality levels were observed with topical surface and 30 days later both topical and impregnated surfaces induced higher mortalities than feeding. Oral treatment inhibited oviposition even at lower doses, and hatching of eggs deposited by treated females was similarly affected by the three delivery modes. Topical treatment of eggs deposited by nontreated females significantly reduced hatching. However, treatment per contact of eggs oviposited by untreated females did not disrupt eclosion. Additionally, oral treatment increased the number of immature oocytes per female, and topical treatment reduced the mean size of oocytes. TFM also affected carcass chitin content, diuresis, and innate immunity of treated insects. These results suggest that TFM acts as a potent growth inhibitor of R. prolixus adult females and has the potential to be used in integrated vector control programs against hematophagous triatomine species.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2016/8603140</identifier><identifier>PMID: 27822479</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Animals ; Benzamides - pharmacology ; Bioassays ; Chitin ; Chitin - metabolism ; Diuresis - drug effects ; Drug dosages ; Eggs ; Feeding Methods ; Female ; Health aspects ; Immunity, Innate - drug effects ; Insecticides - pharmacology ; Insects ; Mortality ; Oocytes - drug effects ; Oviposition - drug effects ; Physiological aspects ; Physiology ; Reproduction - drug effects ; Rhodnius - drug effects ; Rhodnius prolixus ; Transdermal medication ; Vectors (Biology)</subject><ispartof>BioMed research international, 2016-01, Vol.2016 (2016), p.1-11</ispartof><rights>Copyright © 2016 Bianca Santos Henriques et al.</rights><rights>COPYRIGHT 2016 John Wiley & Sons, Inc.</rights><rights>Copyright © 2016 Bianca Santos Henriques et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2016 Bianca Santos Henriques et al. 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-cc03117ce7ac018fee32a9ffe2a9a20964b0d089cdfe9be72b55a6eae15e97103</citedby><cites>FETCH-LOGICAL-c494t-cc03117ce7ac018fee32a9ffe2a9a20964b0d089cdfe9be72b55a6eae15e97103</cites><orcidid>0000-0001-9558-1116 ; 0000-0003-4148-274X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086386/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086386/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27822479$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Cabaret, Jacques</contributor><creatorcontrib>Feder, Denise</creatorcontrib><creatorcontrib>Gonzalez, Marcelo Salabert</creatorcontrib><creatorcontrib>Azambuja, Patricia</creatorcontrib><creatorcontrib>Valle, Denise</creatorcontrib><creatorcontrib>Marinho, Lourena Pinheiro</creatorcontrib><creatorcontrib>Oliveira, Alyne F. 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One day after treatment, the highest mortality levels were observed with topical surface and 30 days later both topical and impregnated surfaces induced higher mortalities than feeding. Oral treatment inhibited oviposition even at lower doses, and hatching of eggs deposited by treated females was similarly affected by the three delivery modes. Topical treatment of eggs deposited by nontreated females significantly reduced hatching. However, treatment per contact of eggs oviposited by untreated females did not disrupt eclosion. Additionally, oral treatment increased the number of immature oocytes per female, and topical treatment reduced the mean size of oocytes. TFM also affected carcass chitin content, diuresis, and innate immunity of treated insects. These results suggest that TFM acts as a potent growth inhibitor of R. prolixus adult females and has the potential to be used in integrated vector control programs against hematophagous triatomine species.</description><subject>Animals</subject><subject>Benzamides - pharmacology</subject><subject>Bioassays</subject><subject>Chitin</subject><subject>Chitin - metabolism</subject><subject>Diuresis - drug effects</subject><subject>Drug dosages</subject><subject>Eggs</subject><subject>Feeding Methods</subject><subject>Female</subject><subject>Health aspects</subject><subject>Immunity, Innate - drug effects</subject><subject>Insecticides - pharmacology</subject><subject>Insects</subject><subject>Mortality</subject><subject>Oocytes - drug effects</subject><subject>Oviposition - drug effects</subject><subject>Physiological aspects</subject><subject>Physiology</subject><subject>Reproduction - drug effects</subject><subject>Rhodnius - drug effects</subject><subject>Rhodnius prolixus</subject><subject>Transdermal medication</subject><subject>Vectors (Biology)</subject><issn>2314-6133</issn><issn>2314-6141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkt9rFDEQx4Motpx981kWfBH02vzYzSYvwlFaFQqVUh98Crns5DZld3Mmu9X7753jzmvtU0OYGZIP38xMhpC3jJ4yVlVnnDJ5piQVrKQvyDFHP5esZC8PsRBH5CTnO4pLMUm1fE2OeK04L2t9TH7epuC7qZ9SHIoL78GNucBwbKH43m5yiF1cbQo7NMUNrFNsJjcGvI--uGljM4QpF3jchT8YLJqpG4tL6G0H-Q155W2X4WTvZ-TH5cXt-df51fWXb-eLq7krdTnOncPkWe2gto4y5QEEtxoTQWs5plsuaUOVdo0HvYSaL6vKSrDAKtA1o2JGPu9019Oyh8bBMCbbmXUKvU0bE20w_98MoTWreG8qqqTAPSMf9gIp_pogj6YP2UHX2QHilA1TpSzRaP0MVNRcaU23qu-foHdxSgN2YieopRb6gVphy0wYfMQU3VbULCpOa1YpqZD6tKNcijkn8IfqGDXbOTDbOTD7OUD83eOOHOB_v47Axx3QhqGxv8Mz5fBf8W37iMZKdS3-ApggxAg</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Feder, Denise</creator><creator>Gonzalez, Marcelo Salabert</creator><creator>Azambuja, Patricia</creator><creator>Valle, Denise</creator><creator>Marinho, Lourena Pinheiro</creator><creator>Oliveira, Alyne F. 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R.</au><au>Codogno, Thaís Franco</au><au>Silva, Lucas Rangel</au><au>Mello, Cícero Brasileiro</au><au>Genta, Fernando A.</au><au>Henriques, Bianca Santos</au><au>Lima, José Bento Pereira</au><au>Cabaret, Jacques</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Triflumuron Effects on the Physiology and Reproduction of Rhodnius prolixus Adult Females</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>2016</volume><issue>2016</issue><spage>1</spage><epage>11</epage><pages>1-11</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>We evaluated the efficacy of the growth regulator triflumuron (TFM) in inducing mortality and disrupting both oviposition and egg hatching in Rhodnius prolixus adult females. TFM was administered via feeding, topically or by continuous contact with impregnated surfaces. Feeding resulted in mild biological effects compared with topical and impregnated surfaces. One day after treatment, the highest mortality levels were observed with topical surface and 30 days later both topical and impregnated surfaces induced higher mortalities than feeding. Oral treatment inhibited oviposition even at lower doses, and hatching of eggs deposited by treated females was similarly affected by the three delivery modes. Topical treatment of eggs deposited by nontreated females significantly reduced hatching. However, treatment per contact of eggs oviposited by untreated females did not disrupt eclosion. Additionally, oral treatment increased the number of immature oocytes per female, and topical treatment reduced the mean size of oocytes. TFM also affected carcass chitin content, diuresis, and innate immunity of treated insects. These results suggest that TFM acts as a potent growth inhibitor of R. prolixus adult females and has the potential to be used in integrated vector control programs against hematophagous triatomine species.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>27822479</pmid><doi>10.1155/2016/8603140</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-9558-1116</orcidid><orcidid>https://orcid.org/0000-0003-4148-274X</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Animals Benzamides - pharmacology Bioassays Chitin Chitin - metabolism Diuresis - drug effects Drug dosages Eggs Feeding Methods Female Health aspects Immunity, Innate - drug effects Insecticides - pharmacology Insects Mortality Oocytes - drug effects Oviposition - drug effects Physiological aspects Physiology Reproduction - drug effects Rhodnius - drug effects Rhodnius prolixus Transdermal medication Vectors (Biology) |
title | Triflumuron Effects on the Physiology and Reproduction of Rhodnius prolixus Adult Females |
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