The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis

Liver fibrosis results from chronic injury of hepatocytes and activation of Collagen Type I producing myofibroblasts that produce fibrous scar in liver fibrosis. Myofibroblasts are not present in the normal liver but rapidly appear early in experimental and clinical liver injury. The origin of the m...

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Veröffentlicht in:Differentiation (London) 2016-09, Vol.92 (3), p.84-92
Hauptverfasser: Karin, Daniel, Koyama, Yukinori, Brenner, David, Kisseleva, Tatiana
Format: Artikel
Sprache:eng
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