Expression of B7-1 and B7-2 costimulatory molecules by human gastric epithelial cells: potential role in CD4+ T cell activation during Helicobacter pylori infection

Human gastric mucosal epithelial cells display class II MHC, the expression of which is increased during Helicobacter pylori infection. These observations suggest that the gastric epithelium may participate as antigen-presenting cells (APC) during local immune responses. The increase in class II MHC...

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Veröffentlicht in:	The Journal of clinical investigation 1997-04, Vol.99 (7), p.1628-1636
Hauptverfasser:	Ye, G, Barrera, C, Fan, X, Gourley, W K, Crowe, S E, Ernst, P B, Reyes, V E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - analysis Antigens, CD - physiology B7-1 Antigen - analysis B7-1 Antigen - physiology B7-2 Antigen CD4-Positive T-Lymphocytes - immunology Cell Line Gastric Mucosa - chemistry Helicobacter Infections - immunology Helicobacter pylori Histocompatibility Antigens Class II - analysis Humans Lymphocyte Activation Membrane Glycoproteins - analysis Membrane Glycoproteins - physiology
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