In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

Populations in developed nations throughout the world are rapidly aging, and the search for geroprotectors, or anti-aging interventions, has never been more important. Yet while hundreds of geroprotectors have extended lifespan in animal models, none have yet been approved for widespread use in huma...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2016-09, Vol.8 (9), p.2127-2152
Hauptverfasser:	Aliper, Alexander, Belikov, Aleksey V, Garazha, Andrew, Jellen, Leslie, Artemov, Artem, Suntsova, Maria, Ivanova, Alena, Venkova, Larisa, Borisov, Nicolas, Buzdin, Anton, Mamoshina, Polina, Putin, Evgeny, Swick, Andrew G, Moskalev, Alexey, Zhavoronkov, Alex
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - drug effects Aging - physiology Animals Computer Simulation Humans Longevity - drug effects Longevity - physiology Research Paper
Online-Zugang:	Volltext
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