Potential Role of the Last Half Repeat in TAL Effectors Revealed by a Molecular Simulation Study

TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dy...

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Veröffentlicht in:	BioMed research international 2016-01, Vol.2016 (2016), p.1-11
Hauptverfasser:	Tian, Xu-hong, Hu, Jian-ping, Chang, Shan, Wan, Hua, Wang, Mei-hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Binding Sites Comparative analysis Computer Simulation Crystal structure Crystals Deoxyribonucleic acid DNA DNA - chemistry DNA - genetics DNA - ultrastructure Efficiency Gene expression Genomes Hydrogen bonds Models, Chemical Molecular dynamics Molecular Dynamics Simulation NMR Nuclear magnetic resonance Nucleic Acid Conformation Principal components analysis Protein Binding Protein Structure, Secondary Proteins Researchers Structure Studies Tandem Repeat Sequences Transcription Activator-Like Effectors - chemistry Transcription Activator-Like Effectors - genetics Transcription Activator-Like Effectors - ultrastructure
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