Bioavailable estradiol concentrations are elevated and predict mortality in septic patients: a prospective cohort study

Experimental studies demonstrate beneficial immunological and hemodynamic effects of estradiol in animal models of sepsis. This raises the question whether estradiol contributes to sex differences in the incidence and outcomes of sepsis in humans. Yet, total estradiol levels are elevated in sepsis p...

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Veröffentlicht in:	Critical care (London, England) England), 2016-10, Vol.20 (1), p.335-335, Article 335
Hauptverfasser:	Tsang, Greg, Insel, Michael B, Weis, Justin M, Morgan, Mary Anne M, Gough, Michael S, Frasier, Lauren M, Mack, Cynthia M, Doolin, Kathleen P, Graves, Brian T, Apostolakos, Michael J, Pietropaoli, Anthony P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological Availability Biomarkers - blood Care and treatment Case-Control Studies Cohort Studies Critical care Critical Illness - mortality Estradiol Estradiol - blood Female Genetic aspects Hospital Mortality - trends Humans Male Measurement Middle Aged Physiological aspects Prognosis Prospective Studies Sepsis Shock, Septic - blood Shock, Septic - diagnosis Shock, Septic - mortality
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