Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice

In a proportion of atopic asthmatics, exposure to a relevant antigen is followed by chronic inflammation in the airways leading to altered airway responsiveness (AR). However, the mechanisms underlying the development of airway hyperresponsiveness still remain unclear. To elucidate the relationship...

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Veröffentlicht in:	The Journal of clinical investigation 1996-03, Vol.97 (6), p.1398-1408
Hauptverfasser:	Oshiba, A, Hamelmann, E, Takeda, K, Bradley, K L, Loader, J E, Larsen, G L, Gelfand, E W
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Animals Bronchial Hyperreactivity - immunology Female Hypersensitivity, Immediate - immunology Immunization, Passive Immunoglobulin E - administration & dosage Immunoglobulin E - immunology Immunoglobulin G - administration & dosage Immunoglobulin G - immunology Mice Mice, Inbred BALB C
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