Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees)
Associated joint disorders with popliteal cysts were stated approximately between the ranges of 41-83 % in all reported cases. Combined treatment strategies that eliminate intra-articular pathologies and cyst- associated valve mechanisms are thought to be a good option in treatment of the disease. I...
Gespeichert in:
Veröffentlicht in: | BMC musculoskeletal disorders 2016-10, Vol.17 (1), p.435-435, Article 435 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 435 |
---|---|
container_issue | 1 |
container_start_page | 435 |
container_title | BMC musculoskeletal disorders |
container_volume | 17 |
creator | Saylik, M Gökkuş, K |
description | Associated joint disorders with popliteal cysts were stated approximately between the ranges of 41-83 % in all reported cases. Combined treatment strategies that eliminate intra-articular pathologies and cyst- associated valve mechanisms are thought to be a good option in treatment of the disease. In this study, our main objective is to present clinical results of our combined treatment results, which includes posterior cyst excision with supine arthroscopic intervention, targeting intra-articular pathologies on recalcitrant cases.
One hundred three knees of 100 patients treated with posterior open cystectomy with valve and repair of posterior capsule, in addition to arthroscopic treatment of intra-articular lesions, were included in the study. Preoperative magnetic resonance imaging (MRI) studies were performed in order to evaluate location of Baker cysts behind the knee. Rauschning-Lindgren and Lysholm Knee Scoring Scales were used to assess pre/post-operative knee functions. Mann-Whitney U test was used to evaluate the differences between genders in comparison of Lysholm and Lindgren scores. Mean age within gender groups was compared using independent samples t-test. Wilcoxon test was used to compare the change in Lysholm and Lindgren scores. A p-value of less than 0.05 was considered to show a statistically significant result. Over the 1-year follow-up period, US and MR imaging was performed only with symptomatic patients.
Cyst recurrence was seen only in 2 (1.94 %) patients. Post-operative Lysholm Knee and Lindgren knee scores demonstrated improvement in knee function and general comfort level of the patients.
Our midterm follow-up (Mean: 39 Months) results showed that open cyst excision with valve and capsule repair with knee arthroscopy that targets associated intra-articular pathologies reduced the pain and improved the knee function in those patients.
IV (Retrospective clinical study without comparison group). |
doi_str_mv | 10.1186/s12891-016-1291-5 |
format | Article |
fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5069796</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A470590011</galeid><sourcerecordid>A470590011</sourcerecordid><originalsourceid>FETCH-LOGICAL-c494t-8e9bc0fa7d0be31632cbe9d740ddf9826fb7e5e8de18be205693450b9fbb6b5f3</originalsourceid><addsrcrecordid>eNptkl1vFSEQhjdGYz_0B3hjSLypiVuB5WO5adI0Vk2aeFOvCbDDKe0urLBrcv69HE-trTFcMGGeeWGYt2neEHxKSC8-FkJ7RVpMREtoDfiz5pAwSVrKJHv-KD5ojkq5xZjIvlMvmwMqJRdUyMNmuc5glgnigpJH1txBRm5blg_IbtFaQtygNENEcyoL5JD2WXBLmrbIxAGVdQ4RkMnLTU7FpXmLUkQZnBldWLKpws4UKOiE4A7dRYDy_lXzwpuxwOv7_bj5fvnp-uJLe_Xt89eL86vWMcWWtgdlHfZGDthCR0RHnQU1SIaHwaueCm8lcOgHIL0FirlQHePYKm-tsNx3x83ZXnde7QSDq11mM-o5h8nkrU4m6KeZGG70Jv3UHAsllagCJ_cCOf1YoSx6CsXBOJoIaS2a9B1nlaN9Rd_9g96mNcfa3m9KMikp_0ttzAg6RJ_qvW4nqs-ZxFzVGZFKnf6HqmuAKbgUwYd6_qSA7AtcnUHJ4B96JFjvrKL3VtHVKnpnFb17ytvHn_NQ8ccb3S-kubqa</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1835747725</pqid></control><display><type>article</type><title>Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees)</title><source>PubMed Central (Open Access)</source><source>MEDLINE</source><source>SpringerLink_现刊</source><source>SpringerOpen (Open Access)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Directory of Open Access Journals (Open Access)</source><source>PubMed Central Open Access</source><creator>Saylik, M ; Gökkuş, K</creator><creatorcontrib>Saylik, M ; Gökkuş, K</creatorcontrib><description>Associated joint disorders with popliteal cysts were stated approximately between the ranges of 41-83 % in all reported cases. Combined treatment strategies that eliminate intra-articular pathologies and cyst- associated valve mechanisms are thought to be a good option in treatment of the disease. In this study, our main objective is to present clinical results of our combined treatment results, which includes posterior cyst excision with supine arthroscopic intervention, targeting intra-articular pathologies on recalcitrant cases.
One hundred three knees of 100 patients treated with posterior open cystectomy with valve and repair of posterior capsule, in addition to arthroscopic treatment of intra-articular lesions, were included in the study. Preoperative magnetic resonance imaging (MRI) studies were performed in order to evaluate location of Baker cysts behind the knee. Rauschning-Lindgren and Lysholm Knee Scoring Scales were used to assess pre/post-operative knee functions. Mann-Whitney U test was used to evaluate the differences between genders in comparison of Lysholm and Lindgren scores. Mean age within gender groups was compared using independent samples t-test. Wilcoxon test was used to compare the change in Lysholm and Lindgren scores. A p-value of less than 0.05 was considered to show a statistically significant result. Over the 1-year follow-up period, US and MR imaging was performed only with symptomatic patients.
Cyst recurrence was seen only in 2 (1.94 %) patients. Post-operative Lysholm Knee and Lindgren knee scores demonstrated improvement in knee function and general comfort level of the patients.
Our midterm follow-up (Mean: 39 Months) results showed that open cyst excision with valve and capsule repair with knee arthroscopy that targets associated intra-articular pathologies reduced the pain and improved the knee function in those patients.
IV (Retrospective clinical study without comparison group).</description><identifier>ISSN: 1471-2474</identifier><identifier>EISSN: 1471-2474</identifier><identifier>DOI: 10.1186/s12891-016-1291-5</identifier><identifier>PMID: 27756267</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arthralgia - etiology ; Arthralgia - surgery ; Arthritis ; Arthroscopy ; Arthroscopy - methods ; Care and treatment ; Cartilage ; Cystectomy ; Cysts ; Endoscopic surgery ; Female ; Follow-Up Studies ; Humans ; Joint Diseases - complications ; Joint Diseases - diagnostic imaging ; Joint Diseases - surgery ; Joints ; Knee ; Knee Joint - diagnostic imaging ; Knee Joint - pathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Orthopedic Procedures - methods ; Patient outcomes ; Patient Positioning ; Popliteal Cyst - complications ; Popliteal Cyst - diagnostic imaging ; Popliteal Cyst - surgery ; Postoperative Period ; Preoperative Care - methods ; Retrospective Studies ; Supine Position ; Treatment Outcome ; Ultrasonography ; Urological surgery</subject><ispartof>BMC musculoskeletal disorders, 2016-10, Vol.17 (1), p.435-435, Article 435</ispartof><rights>COPYRIGHT 2016 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2016</rights><rights>The Author(s). 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-8e9bc0fa7d0be31632cbe9d740ddf9826fb7e5e8de18be205693450b9fbb6b5f3</citedby><cites>FETCH-LOGICAL-c494t-8e9bc0fa7d0be31632cbe9d740ddf9826fb7e5e8de18be205693450b9fbb6b5f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069796/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069796/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27756267$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saylik, M</creatorcontrib><creatorcontrib>Gökkuş, K</creatorcontrib><title>Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees)</title><title>BMC musculoskeletal disorders</title><addtitle>BMC Musculoskelet Disord</addtitle><description>Associated joint disorders with popliteal cysts were stated approximately between the ranges of 41-83 % in all reported cases. Combined treatment strategies that eliminate intra-articular pathologies and cyst- associated valve mechanisms are thought to be a good option in treatment of the disease. In this study, our main objective is to present clinical results of our combined treatment results, which includes posterior cyst excision with supine arthroscopic intervention, targeting intra-articular pathologies on recalcitrant cases.
One hundred three knees of 100 patients treated with posterior open cystectomy with valve and repair of posterior capsule, in addition to arthroscopic treatment of intra-articular lesions, were included in the study. Preoperative magnetic resonance imaging (MRI) studies were performed in order to evaluate location of Baker cysts behind the knee. Rauschning-Lindgren and Lysholm Knee Scoring Scales were used to assess pre/post-operative knee functions. Mann-Whitney U test was used to evaluate the differences between genders in comparison of Lysholm and Lindgren scores. Mean age within gender groups was compared using independent samples t-test. Wilcoxon test was used to compare the change in Lysholm and Lindgren scores. A p-value of less than 0.05 was considered to show a statistically significant result. Over the 1-year follow-up period, US and MR imaging was performed only with symptomatic patients.
Cyst recurrence was seen only in 2 (1.94 %) patients. Post-operative Lysholm Knee and Lindgren knee scores demonstrated improvement in knee function and general comfort level of the patients.
Our midterm follow-up (Mean: 39 Months) results showed that open cyst excision with valve and capsule repair with knee arthroscopy that targets associated intra-articular pathologies reduced the pain and improved the knee function in those patients.
IV (Retrospective clinical study without comparison group).</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arthralgia - etiology</subject><subject>Arthralgia - surgery</subject><subject>Arthritis</subject><subject>Arthroscopy</subject><subject>Arthroscopy - methods</subject><subject>Care and treatment</subject><subject>Cartilage</subject><subject>Cystectomy</subject><subject>Cysts</subject><subject>Endoscopic surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Joint Diseases - complications</subject><subject>Joint Diseases - diagnostic imaging</subject><subject>Joint Diseases - surgery</subject><subject>Joints</subject><subject>Knee</subject><subject>Knee Joint - diagnostic imaging</subject><subject>Knee Joint - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Orthopedic Procedures - methods</subject><subject>Patient outcomes</subject><subject>Patient Positioning</subject><subject>Popliteal Cyst - complications</subject><subject>Popliteal Cyst - diagnostic imaging</subject><subject>Popliteal Cyst - surgery</subject><subject>Postoperative Period</subject><subject>Preoperative Care - methods</subject><subject>Retrospective Studies</subject><subject>Supine Position</subject><subject>Treatment Outcome</subject><subject>Ultrasonography</subject><subject>Urological surgery</subject><issn>1471-2474</issn><issn>1471-2474</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkl1vFSEQhjdGYz_0B3hjSLypiVuB5WO5adI0Vk2aeFOvCbDDKe0urLBrcv69HE-trTFcMGGeeWGYt2neEHxKSC8-FkJ7RVpMREtoDfiz5pAwSVrKJHv-KD5ojkq5xZjIvlMvmwMqJRdUyMNmuc5glgnigpJH1txBRm5blg_IbtFaQtygNENEcyoL5JD2WXBLmrbIxAGVdQ4RkMnLTU7FpXmLUkQZnBldWLKpws4UKOiE4A7dRYDy_lXzwpuxwOv7_bj5fvnp-uJLe_Xt89eL86vWMcWWtgdlHfZGDthCR0RHnQU1SIaHwaueCm8lcOgHIL0FirlQHePYKm-tsNx3x83ZXnde7QSDq11mM-o5h8nkrU4m6KeZGG70Jv3UHAsllagCJ_cCOf1YoSx6CsXBOJoIaS2a9B1nlaN9Rd_9g96mNcfa3m9KMikp_0ttzAg6RJ_qvW4nqs-ZxFzVGZFKnf6HqmuAKbgUwYd6_qSA7AtcnUHJ4B96JFjvrKL3VtHVKnpnFb17ytvHn_NQ8ccb3S-kubqa</recordid><startdate>20161018</startdate><enddate>20161018</enddate><creator>Saylik, M</creator><creator>Gökkuş, K</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20161018</creationdate><title>Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees)</title><author>Saylik, M ; Gökkuş, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-8e9bc0fa7d0be31632cbe9d740ddf9826fb7e5e8de18be205693450b9fbb6b5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arthralgia - etiology</topic><topic>Arthralgia - surgery</topic><topic>Arthritis</topic><topic>Arthroscopy</topic><topic>Arthroscopy - methods</topic><topic>Care and treatment</topic><topic>Cartilage</topic><topic>Cystectomy</topic><topic>Cysts</topic><topic>Endoscopic surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Joint Diseases - complications</topic><topic>Joint Diseases - diagnostic imaging</topic><topic>Joint Diseases - surgery</topic><topic>Joints</topic><topic>Knee</topic><topic>Knee Joint - diagnostic imaging</topic><topic>Knee Joint - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Orthopedic Procedures - methods</topic><topic>Patient outcomes</topic><topic>Patient Positioning</topic><topic>Popliteal Cyst - complications</topic><topic>Popliteal Cyst - diagnostic imaging</topic><topic>Popliteal Cyst - surgery</topic><topic>Postoperative Period</topic><topic>Preoperative Care - methods</topic><topic>Retrospective Studies</topic><topic>Supine Position</topic><topic>Treatment Outcome</topic><topic>Ultrasonography</topic><topic>Urological surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saylik, M</creatorcontrib><creatorcontrib>Gökkuş, K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC musculoskeletal disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saylik, M</au><au>Gökkuş, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees)</atitle><jtitle>BMC musculoskeletal disorders</jtitle><addtitle>BMC Musculoskelet Disord</addtitle><date>2016-10-18</date><risdate>2016</risdate><volume>17</volume><issue>1</issue><spage>435</spage><epage>435</epage><pages>435-435</pages><artnum>435</artnum><issn>1471-2474</issn><eissn>1471-2474</eissn><abstract>Associated joint disorders with popliteal cysts were stated approximately between the ranges of 41-83 % in all reported cases. Combined treatment strategies that eliminate intra-articular pathologies and cyst- associated valve mechanisms are thought to be a good option in treatment of the disease. In this study, our main objective is to present clinical results of our combined treatment results, which includes posterior cyst excision with supine arthroscopic intervention, targeting intra-articular pathologies on recalcitrant cases.
One hundred three knees of 100 patients treated with posterior open cystectomy with valve and repair of posterior capsule, in addition to arthroscopic treatment of intra-articular lesions, were included in the study. Preoperative magnetic resonance imaging (MRI) studies were performed in order to evaluate location of Baker cysts behind the knee. Rauschning-Lindgren and Lysholm Knee Scoring Scales were used to assess pre/post-operative knee functions. Mann-Whitney U test was used to evaluate the differences between genders in comparison of Lysholm and Lindgren scores. Mean age within gender groups was compared using independent samples t-test. Wilcoxon test was used to compare the change in Lysholm and Lindgren scores. A p-value of less than 0.05 was considered to show a statistically significant result. Over the 1-year follow-up period, US and MR imaging was performed only with symptomatic patients.
Cyst recurrence was seen only in 2 (1.94 %) patients. Post-operative Lysholm Knee and Lindgren knee scores demonstrated improvement in knee function and general comfort level of the patients.
Our midterm follow-up (Mean: 39 Months) results showed that open cyst excision with valve and capsule repair with knee arthroscopy that targets associated intra-articular pathologies reduced the pain and improved the knee function in those patients.
IV (Retrospective clinical study without comparison group).</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>27756267</pmid><doi>10.1186/s12891-016-1291-5</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1471-2474 |
ispartof | BMC musculoskeletal disorders, 2016-10, Vol.17 (1), p.435-435, Article 435 |
issn | 1471-2474 1471-2474 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5069796 |
source | PubMed Central (Open Access); MEDLINE; SpringerLink_现刊; SpringerOpen (Open Access); EZB-FREE-00999 freely available EZB journals; Directory of Open Access Journals (Open Access); PubMed Central Open Access |
subjects | Adult Aged Aged, 80 and over Arthralgia - etiology Arthralgia - surgery Arthritis Arthroscopy Arthroscopy - methods Care and treatment Cartilage Cystectomy Cysts Endoscopic surgery Female Follow-Up Studies Humans Joint Diseases - complications Joint Diseases - diagnostic imaging Joint Diseases - surgery Joints Knee Knee Joint - diagnostic imaging Knee Joint - pathology Magnetic Resonance Imaging Male Middle Aged Orthopedic Procedures - methods Patient outcomes Patient Positioning Popliteal Cyst - complications Popliteal Cyst - diagnostic imaging Popliteal Cyst - surgery Postoperative Period Preoperative Care - methods Retrospective Studies Supine Position Treatment Outcome Ultrasonography Urological surgery |
title | Treatment of baker cyst, by using open posterior cystectomy and supine arthroscopy on recalcitrant cases (103 knees) |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T05%3A45%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Treatment%20of%20baker%20cyst,%20by%20using%20open%20posterior%20cystectomy%20and%20supine%20arthroscopy%20on%20recalcitrant%20cases%20(103%20knees)&rft.jtitle=BMC%20musculoskeletal%20disorders&rft.au=Saylik,%20M&rft.date=2016-10-18&rft.volume=17&rft.issue=1&rft.spage=435&rft.epage=435&rft.pages=435-435&rft.artnum=435&rft.issn=1471-2474&rft.eissn=1471-2474&rft_id=info:doi/10.1186/s12891-016-1291-5&rft_dat=%3Cgale_pubme%3EA470590011%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1835747725&rft_id=info:pmid/27756267&rft_galeid=A470590011&rfr_iscdi=true |