Repeated Duplication of Argonaute2 Is Associated with Strong Selection and Testis Specialization in Drosophila

Argonaute2 (Ago2) is a rapidly evolving nuclease in the Drosophila melanogaster RNA interference (RNAi) pathway that targets viruses and transposable elements in somatic tissues. Here we reconstruct the history of Ago2 duplications across the D. obscura group and use patterns of gene expression to i...

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Veröffentlicht in:	Genetics (Austin) 2016-10, Vol.204 (2), p.757-769
Hauptverfasser:	Lewis, Samuel H, Webster, Claire L, Salmela, Heli, Obbard, Darren J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Argonaute Proteins - genetics DNA Transposable Elements - genetics Drosophila melanogaster Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila Proteins - genetics Evolution Evolution, Molecular Females Gene Duplication - genetics Gene expression Gene Expression Regulation, Developmental Genetic engineering Genetics, Population Genome, Insect Genomes Genomics Insects Investigations Male Organ Specificity - genetics Selection, Genetic - genetics Sequence Homology Specialization Testis - growth & development Viruses
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