HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series

Background Carriage of the HLA-Cw*0602 allele is associated with a particular set of clinical features and treatment responses in psoriasis. Tonsillectomy can improve psoriasis. Objectives We sought to evaluate whether HLA-Cw*0602 predicts a favorable outcome after tonsillectomy of patients with pso...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 2016-11, Vol.75 (5), p.889-896
Hauptverfasser:	Thorleifsdottir, Ragna H., MD, Sigurdardottir, Sigrun L., PhD, Sigurgeirsson, Bardur, MD, PhD, Olafsson, Jon H., MD, PhD, Petersen, Hannes, MD, PhD, Sigurdsson, Martin I., MD, PhD, Gudjonsson, Johann E., MD, PhD, Johnston, Andrew, PhD, Valdimarsson, Helgi, MD, FRCP
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Alleles chronic plaque psoriasis Dermatology Female Follow-Up Studies HLA-C Antigens - genetics HLA-Cw0602 Humans Male Pharyngitis - complications Pharyngitis - genetics Pharyngitis - microbiology Prognosis Prospective Studies Psoriasis - etiology Psoriasis - genetics Psoriasis Disability Index Psoriasis Life Stress Inventory Severity of Illness Index sore throat Streptococcal Infections - complications Streptococcal Infections - genetics streptococcal throat infection Tonsillectomy Tonsillitis - complications Tonsillitis - genetics Tonsillitis - microbiology Tonsillitis - surgery Treatment Outcome Young Adult
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