Stable Radiolabeling of Sulfur-Functionalized Silica Nanoparticles with Copper-64

Nanoparticles labeled with radiometals enable whole-body nuclear imaging and therapy. Though chelating agents are commonly used to radiolabel biomolecules, nanoparticles offer the advantage of attaching a radiometal directly to the nanoparticle itself without the need of such agents. We previously d...

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Veröffentlicht in:	Nano letters 2016-09, Vol.16 (9), p.5601-5604
Hauptverfasser:	Shaffer, Travis M, Harmsen, Stefan, Khwaja, Emaad, Kircher, Moritz F, Drain, Charles Michael, Grimm, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Copper Radioisotopes - chemistry Male Mice, Nude Nanoparticles - chemistry Positron-Emission Tomography Silicon Dioxide Sulfur - chemistry
Online-Zugang:	Volltext
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