Non-equilibrium plasma prevention of Schistosoma japonicum transmission
Schistosoma japonicum is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting th...
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| Veröffentlicht in: | Scientific reports 2016-10, Vol.6 (1), p.35353-35353, Article 35353 |
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| creator | Wang, Xing-Quan Wang, Feng-Peng Chen, Wei Huang, Jun Bazaka, Kateryna Ostrikov, Kostya (Ken) |
| description | Schistosoma japonicum
is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting the parasite. Infection occurs when a host comes into contact with cercariae, a planktonic larval stage of the parasite, and can be prevented by inactivating the larvae, commonly by chemical treatment. We investigated the use of physical non-equilibrium plasma generated at atmospheric pressure using custom-made dielectric barrier discharge reactor to kill
S. japonicum
cercariae. Survival rate decreased with treatment time and applied power. Plasmas generated in O
2
and air gas discharges were more effective in killing
S. japonicum
cercariae than that generated in He, which is directly related to the mechanism by which cercariae are inactivated. Reactive oxygen species, such as O atoms, abundant in O
2
plasma and NO in air plasma play a major role in killing of
S. japonicum
cercariae via oxidation mechanisms. Similar level of efficacy is also shown for a gliding arc discharge plasma jet generated in ambient air, a system that may be more appropriate for scale-up and integration into existing water treatment processes. |
| doi_str_mv | 10.1038/srep35353 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5064309</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1899120740</sourcerecordid><originalsourceid>FETCH-LOGICAL-c504t-57b60319c57ab7bfec12c4f019b079ef33a44c989a927e725ba3699b0c31e3d73</originalsourceid><addsrcrecordid>eNplkUtLAzEUhYMoKtqFf0AKblQYzbNpNoKILyi6UNchEzNtykwyTWYE_71XWkvVZJHA-Tj3XA5CRwRfEMzGlzm5lgm4W2ifYi4Kyijd3vjvoUHOcwxHUMWJ2kV7VEqmuFD76P4phsItel_7Mvm-Gba1yY0Ztsl9uND5GIaxGr7Ymc9dzBGUuWlj8BbQLpmQG58zUIdopzJ1doPVe4De7m5fbx6KyfP94831pLAC864QshxhRpQV0pSyrJwl1PIKE1ViqVzFmOHcqrEyikonqSgNGykQLSOOvUt2gK6Wvm1fNu7dQsZkat0m35j0qaPx-rcS_ExP44cWeMQZVmBwujJIcdG73GnYwLq6NsHFPmsyZoITPsYM0JM_6Dz2KcB6QClFKJYcA3W2pGyKGcqo1mEI1t8N6XVDwB5vpl-TP30AcL4EMkhh6tLGyH9uX6wFm2E</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1899120740</pqid></control><display><type>article</type><title>Non-equilibrium plasma prevention of Schistosoma japonicum transmission</title><source>MEDLINE</source><source>Nature Free</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature OA Free Journals</source><creator>Wang, Xing-Quan ; Wang, Feng-Peng ; Chen, Wei ; Huang, Jun ; Bazaka, Kateryna ; Ostrikov, Kostya (Ken)</creator><creatorcontrib>Wang, Xing-Quan ; Wang, Feng-Peng ; Chen, Wei ; Huang, Jun ; Bazaka, Kateryna ; Ostrikov, Kostya (Ken)</creatorcontrib><description>Schistosoma japonicum
is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting the parasite. Infection occurs when a host comes into contact with cercariae, a planktonic larval stage of the parasite, and can be prevented by inactivating the larvae, commonly by chemical treatment. We investigated the use of physical non-equilibrium plasma generated at atmospheric pressure using custom-made dielectric barrier discharge reactor to kill
S. japonicum
cercariae. Survival rate decreased with treatment time and applied power. Plasmas generated in O
2
and air gas discharges were more effective in killing
S. japonicum
cercariae than that generated in He, which is directly related to the mechanism by which cercariae are inactivated. Reactive oxygen species, such as O atoms, abundant in O
2
plasma and NO in air plasma play a major role in killing of
S. japonicum
cercariae via oxidation mechanisms. Similar level of efficacy is also shown for a gliding arc discharge plasma jet generated in ambient air, a system that may be more appropriate for scale-up and integration into existing water treatment processes.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/srep35353</identifier><identifier>PMID: 27739459</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>639/166 ; 639/766/1960 ; Anemia ; Animal parasites ; Animals ; Atmospheric pressure ; Bladder cancer ; Cercaria - radiation effects ; Chemical treatment ; Colon ; Gliding ; Humanities and Social Sciences ; Humans ; Integration ; Intestine ; Larva - pathogenicity ; Larva - radiation effects ; Larvae ; Liver ; Liver - parasitology ; Liver - radiation effects ; multidisciplinary ; Oxidation ; Parasites ; Physical Phenomena ; Plasma ; Reactive oxygen species ; Schistosoma japonicum - pathogenicity ; Schistosoma japonicum - radiation effects ; Schistosomiasis ; Schistosomiasis japonica - parasitology ; Schistosomiasis japonica - prevention & control ; Science ; Survival ; Urinary bladder ; Water treatment</subject><ispartof>Scientific reports, 2016-10, Vol.6 (1), p.35353-35353, Article 35353</ispartof><rights>The Author(s) 2016</rights><rights>Copyright Nature Publishing Group Oct 2016</rights><rights>Copyright © 2016, The Author(s) 2016 The Author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-57b60319c57ab7bfec12c4f019b079ef33a44c989a927e725ba3699b0c31e3d73</citedby><cites>FETCH-LOGICAL-c504t-57b60319c57ab7bfec12c4f019b079ef33a44c989a927e725ba3699b0c31e3d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064309/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064309/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,41096,42165,51551,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27739459$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Xing-Quan</creatorcontrib><creatorcontrib>Wang, Feng-Peng</creatorcontrib><creatorcontrib>Chen, Wei</creatorcontrib><creatorcontrib>Huang, Jun</creatorcontrib><creatorcontrib>Bazaka, Kateryna</creatorcontrib><creatorcontrib>Ostrikov, Kostya (Ken)</creatorcontrib><title>Non-equilibrium plasma prevention of Schistosoma japonicum transmission</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Schistosoma japonicum
is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting the parasite. Infection occurs when a host comes into contact with cercariae, a planktonic larval stage of the parasite, and can be prevented by inactivating the larvae, commonly by chemical treatment. We investigated the use of physical non-equilibrium plasma generated at atmospheric pressure using custom-made dielectric barrier discharge reactor to kill
S. japonicum
cercariae. Survival rate decreased with treatment time and applied power. Plasmas generated in O
2
and air gas discharges were more effective in killing
S. japonicum
cercariae than that generated in He, which is directly related to the mechanism by which cercariae are inactivated. Reactive oxygen species, such as O atoms, abundant in O
2
plasma and NO in air plasma play a major role in killing of
S. japonicum
cercariae via oxidation mechanisms. Similar level of efficacy is also shown for a gliding arc discharge plasma jet generated in ambient air, a system that may be more appropriate for scale-up and integration into existing water treatment processes.</description><subject>639/166</subject><subject>639/766/1960</subject><subject>Anemia</subject><subject>Animal parasites</subject><subject>Animals</subject><subject>Atmospheric pressure</subject><subject>Bladder cancer</subject><subject>Cercaria - radiation effects</subject><subject>Chemical treatment</subject><subject>Colon</subject><subject>Gliding</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Integration</subject><subject>Intestine</subject><subject>Larva - pathogenicity</subject><subject>Larva - radiation effects</subject><subject>Larvae</subject><subject>Liver</subject><subject>Liver - parasitology</subject><subject>Liver - radiation effects</subject><subject>multidisciplinary</subject><subject>Oxidation</subject><subject>Parasites</subject><subject>Physical Phenomena</subject><subject>Plasma</subject><subject>Reactive oxygen species</subject><subject>Schistosoma japonicum - pathogenicity</subject><subject>Schistosoma japonicum - radiation effects</subject><subject>Schistosomiasis</subject><subject>Schistosomiasis japonica - parasitology</subject><subject>Schistosomiasis japonica - prevention & control</subject><subject>Science</subject><subject>Survival</subject><subject>Urinary bladder</subject><subject>Water treatment</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNplkUtLAzEUhYMoKtqFf0AKblQYzbNpNoKILyi6UNchEzNtykwyTWYE_71XWkvVZJHA-Tj3XA5CRwRfEMzGlzm5lgm4W2ifYi4Kyijd3vjvoUHOcwxHUMWJ2kV7VEqmuFD76P4phsItel_7Mvm-Gba1yY0Ztsl9uND5GIaxGr7Ymc9dzBGUuWlj8BbQLpmQG58zUIdopzJ1doPVe4De7m5fbx6KyfP94831pLAC864QshxhRpQV0pSyrJwl1PIKE1ViqVzFmOHcqrEyikonqSgNGykQLSOOvUt2gK6Wvm1fNu7dQsZkat0m35j0qaPx-rcS_ExP44cWeMQZVmBwujJIcdG73GnYwLq6NsHFPmsyZoITPsYM0JM_6Dz2KcB6QClFKJYcA3W2pGyKGcqo1mEI1t8N6XVDwB5vpl-TP30AcL4EMkhh6tLGyH9uX6wFm2E</recordid><startdate>20161014</startdate><enddate>20161014</enddate><creator>Wang, Xing-Quan</creator><creator>Wang, Feng-Peng</creator><creator>Chen, Wei</creator><creator>Huang, Jun</creator><creator>Bazaka, Kateryna</creator><creator>Ostrikov, Kostya (Ken)</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20161014</creationdate><title>Non-equilibrium plasma prevention of Schistosoma japonicum transmission</title><author>Wang, Xing-Quan ; Wang, Feng-Peng ; Chen, Wei ; Huang, Jun ; Bazaka, Kateryna ; Ostrikov, Kostya (Ken)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-57b60319c57ab7bfec12c4f019b079ef33a44c989a927e725ba3699b0c31e3d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>639/166</topic><topic>639/766/1960</topic><topic>Anemia</topic><topic>Animal parasites</topic><topic>Animals</topic><topic>Atmospheric pressure</topic><topic>Bladder cancer</topic><topic>Cercaria - radiation effects</topic><topic>Chemical treatment</topic><topic>Colon</topic><topic>Gliding</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Integration</topic><topic>Intestine</topic><topic>Larva - pathogenicity</topic><topic>Larva - radiation effects</topic><topic>Larvae</topic><topic>Liver</topic><topic>Liver - parasitology</topic><topic>Liver - radiation effects</topic><topic>multidisciplinary</topic><topic>Oxidation</topic><topic>Parasites</topic><topic>Physical Phenomena</topic><topic>Plasma</topic><topic>Reactive oxygen species</topic><topic>Schistosoma japonicum - pathogenicity</topic><topic>Schistosoma japonicum - radiation effects</topic><topic>Schistosomiasis</topic><topic>Schistosomiasis japonica - parasitology</topic><topic>Schistosomiasis japonica - prevention & control</topic><topic>Science</topic><topic>Survival</topic><topic>Urinary bladder</topic><topic>Water treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Xing-Quan</creatorcontrib><creatorcontrib>Wang, Feng-Peng</creatorcontrib><creatorcontrib>Chen, Wei</creatorcontrib><creatorcontrib>Huang, Jun</creatorcontrib><creatorcontrib>Bazaka, Kateryna</creatorcontrib><creatorcontrib>Ostrikov, Kostya (Ken)</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Xing-Quan</au><au>Wang, Feng-Peng</au><au>Chen, Wei</au><au>Huang, Jun</au><au>Bazaka, Kateryna</au><au>Ostrikov, Kostya (Ken)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Non-equilibrium plasma prevention of Schistosoma japonicum transmission</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2016-10-14</date><risdate>2016</risdate><volume>6</volume><issue>1</issue><spage>35353</spage><epage>35353</epage><pages>35353-35353</pages><artnum>35353</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Schistosoma japonicum
is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting the parasite. Infection occurs when a host comes into contact with cercariae, a planktonic larval stage of the parasite, and can be prevented by inactivating the larvae, commonly by chemical treatment. We investigated the use of physical non-equilibrium plasma generated at atmospheric pressure using custom-made dielectric barrier discharge reactor to kill
S. japonicum
cercariae. Survival rate decreased with treatment time and applied power. Plasmas generated in O
2
and air gas discharges were more effective in killing
S. japonicum
cercariae than that generated in He, which is directly related to the mechanism by which cercariae are inactivated. Reactive oxygen species, such as O atoms, abundant in O
2
plasma and NO in air plasma play a major role in killing of
S. japonicum
cercariae via oxidation mechanisms. Similar level of efficacy is also shown for a gliding arc discharge plasma jet generated in ambient air, a system that may be more appropriate for scale-up and integration into existing water treatment processes.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>27739459</pmid><doi>10.1038/srep35353</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 639/166 639/766/1960 Anemia Animal parasites Animals Atmospheric pressure Bladder cancer Cercaria - radiation effects Chemical treatment Colon Gliding Humanities and Social Sciences Humans Integration Intestine Larva - pathogenicity Larva - radiation effects Larvae Liver Liver - parasitology Liver - radiation effects multidisciplinary Oxidation Parasites Physical Phenomena Plasma Reactive oxygen species Schistosoma japonicum - pathogenicity Schistosoma japonicum - radiation effects Schistosomiasis Schistosomiasis japonica - parasitology Schistosomiasis japonica - prevention & control Science Survival Urinary bladder Water treatment |
| title | Non-equilibrium plasma prevention of Schistosoma japonicum transmission |
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