Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders

Neurodegenerative disorders are significantly increasing in incidence as the age of the global population continues to climb with improved life expectancy. At present, more than 30 million individuals throughout the world are impacted by acute and chronic neurodegenerative disorders with limited tre...

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Veröffentlicht in:	British journal of clinical pharmacology 2016-11, Vol.82 (5), p.1245-1266
1. Verfasser:	Maiese, Kenneth
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Apoptosis - drug effects Apoptosis - physiology Autophagy - drug effects Autophagy - physiology erythropoietin Humans Huntington's disease Molecular Targeted Therapy - methods Neurodegenerative Diseases - drug therapy Parkinson's disease Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Review‐themed Issue Signal Transduction - drug effects Signal Transduction - physiology stem cells stroke TOR Serine-Threonine Kinases - antagonists & inhibitors TOR Serine-Threonine Kinases - physiology
Online-Zugang:	Volltext
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