Hypoglycaemia when adding sulphonylurea to metformin: a systematic review and network meta‐analysis

Aims The risk of hypoglycaemia may differ among sulphonylureas (SUs), but evidence from head‐to‐head comparisons is sparse. Performing a network meta‐analysis to use indirect evidence from randomized controlled trials (RCTs), we compared the relative risk of hypoglycaemia with newer generation SUs w...

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Veröffentlicht in:	British journal of clinical pharmacology 2016-11, Vol.82 (5), p.1291-1302
Hauptverfasser:	Andersen, Stig Ejdrup, Christensen, Mikkel
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetes Mellitus, Type 2 - drug therapy Drug Therapy, Combination - adverse effects Humans hypoglycaemia Hypoglycemia - chemically induced Hypoglycemic Agents - adverse effects Metformin - adverse effects Metformin - therapeutic use Network Meta-Analysis oral antiglycaemic agents relative safety Sulfonylurea Compounds - adverse effects sulphonylurea Systematic Review type 2 diabetes
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