Altered oncomodules underlie chromatin regulatory factors driver mutations

Chromatin regulatory factors (CRFs), are known to be involved in tumorigenesis in several cancer types. Nevertheless, the molecular mechanisms through which driver alterations of CRFs cause tumorigenesis remain unknown. Here, we developed a CRFs Oncomodules Discovery approach, which mines several so...

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Veröffentlicht in:Oncotarget 2016-05, Vol.7 (21), p.30748-30759
Hauptverfasser: Frigola, Joan, Iturbide, Ane, Lopez-Bigas, Nuria, Peiro, Sandra, Gonzalez-Perez, Abel
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Sprache:eng
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