Ataxic gait following total gastrectomy for gastric cancer
A 58-year-old woman, who had undergone total gastrectomy for early gastric cancer 9 years previously, visited the outpatient clinic complaining of progressive difficulty in walking for 15 d. Laboratory examinations showed macrocytic anemia and a decreased serum vitamin B12 concentration and increase...
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Veröffentlicht in: | World journal of gastroenterology : WJG 2016-10, Vol.22 (37), p.8435-8438 |
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description | A 58-year-old woman, who had undergone total gastrectomy for early gastric cancer 9 years previously, visited the outpatient clinic complaining of progressive difficulty in walking for 15 d. Laboratory examinations showed macrocytic anemia and a decreased serum vitamin B12 concentration and increased serum concentrations of folate, vitamin E and copper. Magnetic resonance imaging showed multifocal high signal intensities along the posterior column of the cervical and thoracic spinal cord. Treatment consisted of intramuscular injections of vitamin B12 for 7 d, which increased her serum level of vitamin B12 to normal. This was followed by weekly intramuscular injections of vitamin B12 for another 2 wk and oral administration of vitamin B12 three times per day. After comprehensive rehabilitation for 4 wk, she showed sufficient improvements in strength and ataxic gait, enabling her to return to her normal daily activities. |
doi_str_mv | 10.3748/wjg.v22.i37.8435 |
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Laboratory examinations showed macrocytic anemia and a decreased serum vitamin B12 concentration and increased serum concentrations of folate, vitamin E and copper. Magnetic resonance imaging showed multifocal high signal intensities along the posterior column of the cervical and thoracic spinal cord. Treatment consisted of intramuscular injections of vitamin B12 for 7 d, which increased her serum level of vitamin B12 to normal. This was followed by weekly intramuscular injections of vitamin B12 for another 2 wk and oral administration of vitamin B12 three times per day. After comprehensive rehabilitation for 4 wk, she showed sufficient improvements in strength and ataxic gait, enabling her to return to her normal daily activities.</description><identifier>ISSN: 1007-9327</identifier><identifier>EISSN: 2219-2840</identifier><identifier>DOI: 10.3748/wjg.v22.i37.8435</identifier><identifier>PMID: 27729749</identifier><language>eng</language><publisher>United States: Baishideng Publishing Group Inc</publisher><subject>Administration, Oral ; Ataxia - complications ; Ataxia - surgery ; B12 ; cancer ; Case Report ; combined ; deficiency;Total ; degeneration;Vitamin ; Diagnosis, Differential ; Female ; Gait ; Gastrectomy ; gastrectomy;Gastric ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Stomach Neoplasms - complications ; Stomach Neoplasms - surgery ; Subacute ; Treatment Outcome ; Vitamin B 12 - therapeutic use ; Vitamin B 12 Deficiency ; Walking</subject><ispartof>World journal of gastroenterology : WJG, 2016-10, Vol.22 (37), p.8435-8438</ispartof><rights>The Author(s) 2016. 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All rights reserved. 2016</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-141595ed523f3f90af705d15cbd814af6905ba11b27fcfb25978bea77af1a2a13</citedby><cites>FETCH-LOGICAL-c440t-141595ed523f3f90af705d15cbd814af6905ba11b27fcfb25978bea77af1a2a13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84123X/84123X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055873/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055873/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27729749$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hwang, Chang Ho</creatorcontrib><creatorcontrib>Park, Dong Jin</creatorcontrib><creatorcontrib>Kim, Gyu Yeol</creatorcontrib><title>Ataxic gait following total gastrectomy for gastric cancer</title><title>World journal of gastroenterology : WJG</title><addtitle>World Journal of Gastroenterology</addtitle><description>A 58-year-old woman, who had undergone total gastrectomy for early gastric cancer 9 years previously, visited the outpatient clinic complaining of progressive difficulty in walking for 15 d. Laboratory examinations showed macrocytic anemia and a decreased serum vitamin B12 concentration and increased serum concentrations of folate, vitamin E and copper. Magnetic resonance imaging showed multifocal high signal intensities along the posterior column of the cervical and thoracic spinal cord. Treatment consisted of intramuscular injections of vitamin B12 for 7 d, which increased her serum level of vitamin B12 to normal. This was followed by weekly intramuscular injections of vitamin B12 for another 2 wk and oral administration of vitamin B12 three times per day. After comprehensive rehabilitation for 4 wk, she showed sufficient improvements in strength and ataxic gait, enabling her to return to her normal daily activities.</description><subject>Administration, Oral</subject><subject>Ataxia - complications</subject><subject>Ataxia - surgery</subject><subject>B12</subject><subject>cancer</subject><subject>Case Report</subject><subject>combined</subject><subject>deficiency;Total</subject><subject>degeneration;Vitamin</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Gait</subject><subject>Gastrectomy</subject><subject>gastrectomy;Gastric</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Middle Aged</subject><subject>Stomach Neoplasms - complications</subject><subject>Stomach Neoplasms - surgery</subject><subject>Subacute</subject><subject>Treatment Outcome</subject><subject>Vitamin B 12 - therapeutic use</subject><subject>Vitamin B 12 Deficiency</subject><subject>Walking</subject><issn>1007-9327</issn><issn>2219-2840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEtPAyEURonR2PrYuzJdupnK6wq4MDHGV2LiRteEoTBOMx1aoD7-vdTWRtnA5Z77QQ5CJwSPmeDy_GPajN8pHbdMjCVnsIOGlBJVUcnxLhoSjEWlGBUDdJDSFGPKGNB9NKBCUCW4GqLL62w-WztqTJtHPnRd-Gj7ZpRDNl25TDk6m8Psq_Tiui6wNb118QjtedMld7zZD9Hr3e3LzUP19Hz_eHP9VFnOca4IJ6DATYAyz7zCxgsMEwK2nkjCjb9QGGpDSE2Ft76moISsnRHCeGKoIewQXa1z58t65ibW9TmaTs9jOzPxSwfT6v-dvn3TTXjXgAGkYCXgbBMQw2LpUtazNlnXdaZ3YZk0kQw4pheEFhSvURtDStH57TME65VyXZTrolwX5XqlvIyc_v3eduDXcQHYJvMt9M2i6N0yCsvVUoC55Ao4EICfk2DfM72Oew</recordid><startdate>20161007</startdate><enddate>20161007</enddate><creator>Hwang, Chang Ho</creator><creator>Park, Dong Jin</creator><creator>Kim, Gyu Yeol</creator><general>Baishideng Publishing Group Inc</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20161007</creationdate><title>Ataxic gait following total gastrectomy for gastric cancer</title><author>Hwang, Chang Ho ; Park, Dong Jin ; Kim, Gyu Yeol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-141595ed523f3f90af705d15cbd814af6905ba11b27fcfb25978bea77af1a2a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Administration, Oral</topic><topic>Ataxia - complications</topic><topic>Ataxia - surgery</topic><topic>B12</topic><topic>cancer</topic><topic>Case Report</topic><topic>combined</topic><topic>deficiency;Total</topic><topic>degeneration;Vitamin</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Gait</topic><topic>Gastrectomy</topic><topic>gastrectomy;Gastric</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Middle Aged</topic><topic>Stomach Neoplasms - complications</topic><topic>Stomach Neoplasms - surgery</topic><topic>Subacute</topic><topic>Treatment Outcome</topic><topic>Vitamin B 12 - therapeutic use</topic><topic>Vitamin B 12 Deficiency</topic><topic>Walking</topic><toplevel>online_resources</toplevel><creatorcontrib>Hwang, Chang Ho</creatorcontrib><creatorcontrib>Park, Dong Jin</creatorcontrib><creatorcontrib>Kim, Gyu Yeol</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>World journal of gastroenterology : WJG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hwang, Chang Ho</au><au>Park, Dong Jin</au><au>Kim, Gyu Yeol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ataxic gait following total gastrectomy for gastric cancer</atitle><jtitle>World journal of gastroenterology : WJG</jtitle><addtitle>World Journal of Gastroenterology</addtitle><date>2016-10-07</date><risdate>2016</risdate><volume>22</volume><issue>37</issue><spage>8435</spage><epage>8438</epage><pages>8435-8438</pages><issn>1007-9327</issn><eissn>2219-2840</eissn><abstract>A 58-year-old woman, who had undergone total gastrectomy for early gastric cancer 9 years previously, visited the outpatient clinic complaining of progressive difficulty in walking for 15 d. Laboratory examinations showed macrocytic anemia and a decreased serum vitamin B12 concentration and increased serum concentrations of folate, vitamin E and copper. Magnetic resonance imaging showed multifocal high signal intensities along the posterior column of the cervical and thoracic spinal cord. Treatment consisted of intramuscular injections of vitamin B12 for 7 d, which increased her serum level of vitamin B12 to normal. This was followed by weekly intramuscular injections of vitamin B12 for another 2 wk and oral administration of vitamin B12 three times per day. After comprehensive rehabilitation for 4 wk, she showed sufficient improvements in strength and ataxic gait, enabling her to return to her normal daily activities.</abstract><cop>United States</cop><pub>Baishideng Publishing Group Inc</pub><pmid>27729749</pmid><doi>10.3748/wjg.v22.i37.8435</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Administration, Oral Ataxia - complications Ataxia - surgery B12 cancer Case Report combined deficiency Total degeneration Vitamin Diagnosis, Differential Female Gait Gastrectomy gastrectomy Gastric Humans Magnetic Resonance Imaging Middle Aged Stomach Neoplasms - complications Stomach Neoplasms - surgery Subacute Treatment Outcome Vitamin B 12 - therapeutic use Vitamin B 12 Deficiency Walking |
title | Ataxic gait following total gastrectomy for gastric cancer |
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