Chromatin Immunoprecipitation Sequencing Technology Reveals Global Regulatory Roles of Low-Cell-Density Quorum-Sensing Regulator AphA in the Pathogen Vibrio alginolyticus

Quorum sensing (QS) is an important regulatory system in virulence expression and environmental adaptation in bacteria. The master QS regulators (MQSR) LuxR and AphA reciprocally control QS gene expression in vibrios. However, the molecular basis for the regulatory functions of AphA remains undefine...

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Veröffentlicht in:	Journal of bacteriology 2016-11, Vol.198 (21), p.2985-2999
Hauptverfasser:	Gu, Dan, Liu, Huan, Yang, Zhen, Zhang, Yuanxing, Wang, Qiyao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal diseases Bacteria Bacteriology Biofilms Chromatin Chromatin Immunoprecipitation Deoxyribonucleic acid DNA Gene expression Gene Expression Regulation, Bacterial High-Throughput Nucleotide Sequencing Mutagenesis Pathogens Polymerase chain reaction Promoter Regions, Genetic Quorum Sensing Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - metabolism Vibrio alginolyticus Vibrio alginolyticus - genetics Vibrio alginolyticus - growth & development Vibrio alginolyticus - metabolism Vibrio alginolyticus - pathogenicity Virulence
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