Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population

The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially functional single nucleotide polymorphisms (SNPs) of four essential genes in the pathway and GCa risk in a stud...

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Veröffentlicht in:	Oncotarget 2016-05, Vol.7 (19), p.28112-28123
Hauptverfasser:	Zhou, Fei, Cheng, Lei, Qiu, Li-Xin, Wang, Meng-Yun, Li, Jin, Sun, Meng-Hong, Yang, Ya-Jun, Wang, Jiu-Cun, Jin, Li, Wang, Ya-Nong, Wei, Qing-Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adult Aged Aged, 80 and over Asian Continental Ancestry Group - genetics Case-Control Studies Female Genetic Predisposition to Disease Genotype Humans Interleukin-6 - genetics Janus Kinase 1 - genetics Male Middle Aged Polymorphism, Single Nucleotide Research Paper Risk Factors STAT3 Transcription Factor - genetics Stomach Neoplasms - genetics Young Adult
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