DARS: a phase III randomised multicentre study of dysphagia- optimised intensity- modulated radiotherapy (Do-IMRT) versus standard intensity- modulated radiotherapy (S-IMRT) in head and neck cancer

Persistent dysphagia following primary chemoradiation (CRT) for head and neck cancers can have a devastating impact on patients' quality of life. Single arm studies have shown that the dosimetric sparing of critical swallowing structures such as the pharyngeal constrictor muscle and supraglotti...

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Veröffentlicht in:	BMC cancer 2016-10, Vol.16 (1), p.770, Article 770
Hauptverfasser:	Petkar, Imran, Rooney, Keith, Roe, Justin W G, Patterson, Joanne M, Bernstein, David, Tyler, Justine M, Emson, Marie A, Morden, James P, Mertens, Kathrin, Miles, Elizabeth, Beasley, Matthew, Roques, Tom, Bhide, Shreerang A, Newbold, Kate L, Harrington, Kevin J, Hall, Emma, Nutting, Christopher M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cancer therapies Carcinoma, Squamous Cell - radiotherapy Care and treatment Chemoradiotherapy Chemotherapy Clinical Trials, Phase III as Topic Complications and side effects Consent Deglutition disorders Deglutition Disorders - etiology Deglutition Disorders - prevention & control Diagnosis Dosimetry Dysphagia Endoscopy Funding Head & neck cancer Head and Neck Neoplasms - radiotherapy Human papillomavirus Humans Larynx Lymphatic system Medical research Multicenter Studies as Topic Patients Pneumonia Quality control Quality of Life Radiation Injuries - etiology Radiation Injuries - prevention & control Radiation therapy Radiotherapy Radiotherapy, Intensity-Modulated - adverse effects Randomized Controlled Trials as Topic Speech therapists Squamous Cell Carcinoma of Head and Neck Studies Study Protocol Throat cancer Tumors
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