Impact of In Utero Exposure to Malaria on Fetal T Cell Immunity

Pregnancy-associated malaria, including placental malaria, causes significant morbidity and mortality worldwide. Recently, it has been suggested that in utero exposure of the fetus to malaria antigens may negatively impact the developing immune system and result in tolerance to malaria. Here, we rev...

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Veröffentlicht in:	Trends in molecular medicine 2016-10, Vol.22 (10), p.877-888
Hauptverfasser:	Odorizzi, Pamela M, Feeney, Margaret E
Format:	Artikel
Sprache:	eng
Schlagworte:	Female fetal immune system fetal tolerance Fetus - cytology Fetus - immunology Fetus - pathology Humans Immune Tolerance Immunity Immunity, Cellular Immunity, Innate Infectious Disease Transmission, Vertical Malaria - complications Malaria - epidemiology Malaria - immunology Malaria - pathology Pathology placental malaria Pregnancy Pregnancy Complications, Parasitic - epidemiology Pregnancy Complications, Parasitic - immunology Pregnancy Complications, Parasitic - pathology pregnancy-associated malaria Prenatal Exposure Delayed Effects - epidemiology Prenatal Exposure Delayed Effects - immunology Prenatal Exposure Delayed Effects - pathology T-Lymphocytes - immunology
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