Pre-fusion F is absent on the surface of formalin-inactivated respiratory syncytial virus

The lack of a licensed vaccine for respiratory syncytial virus (RSV) can be partly attributed to regulatory hurdles resulting from vaccine enhanced respiratory disease (ERD) subsequent to natural RSV infection that was observed in clinical trials of formalin-inactivated RSV (FI-RSV) in antigen-naïve...

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Veröffentlicht in:	Scientific reports 2016-09, Vol.6 (1), p.34108-34108, Article 34108
Hauptverfasser:	Killikelly, April M., Kanekiyo, Masaru, Graham, Barney S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/590 631/250/590/2294 82 82/1 Antigenicity Antigens Clinical trials Conformation Formaldehyde Heat inactivation Humanities and Social Sciences Immunogenicity Inactivation Infants multidisciplinary Respiratory diseases Respiratory syncytial virus Science Vaccines Virions
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