Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1

Some adult-onset disorders may be linked to dysregulated embryonic development, yet the mechanisms underlying this association remain poorly understood. Congenital retinal degenerative diseases are blinding disorders characterized by postnatal degeneration of photoreceptors, and affect nearly 2 mill...

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Veröffentlicht in:	Scientific reports 2016-09, Vol.6 (1), p.33887-33887, Article 33887
Hauptverfasser:	Yan, Naihong, Cheng, Lin, Cho, Kinsang, Malik, Muhammad Taimur A., Xiao, Lirong, Guo, Chenying, Yu, Honghua, Zhu, Ruilin, Rao, Rajesh C., Chen, Dong Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	14/63 38/15 38/61 45/29 631/80/304 64/60 692/699/3161/3175 Degenerative diseases Derepression Embryogenesis Embryonic growth stage Fetuses Gene deletion Histone methyltransferase Homeostasis Humanities and Social Sciences multidisciplinary Photoreceptors Retina Retinal degeneration Science Science (multidisciplinary)
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