Noninvasive diagnosis of vulnerable coronary plaque

Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease.For this reason,screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine.Necropsy studies have described histopathological...

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Veröffentlicht in:World journal of cardiology 2016-09, Vol.8 (9), p.520-533
Hauptverfasser: Pozo, Eduardo, Agudo-Quilez, Pilar, Rojas-González, Antonio, Alvarado, Teresa, Olivera, María José, Jiménez-Borreguero, Luis Jesús, Alfonso, Fernando
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container_end_page 533
container_issue 9
container_start_page 520
container_title World journal of cardiology
container_volume 8
creator Pozo, Eduardo
Agudo-Quilez, Pilar
Rojas-González, Antonio
Alvarado, Teresa
Olivera, María José
Jiménez-Borreguero, Luis Jesús
Alfonso, Fernando
description Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease.For this reason,screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine.Necropsy studies have described histopathological changes associated with the development of acute coronary events.In this regard,thin-cap fibroatheroma has been identified as the main vulnerable coronary plaque feature.Hence,many imaging techniques,such as coronary computed tomography,cardiac magnetic resonance or positron emission tomography,have tried to detect noninvasively these histomorphological characteristics with different approaches.In this article,we review the role of these diagnostic tools in the detection of vulnerable coronary plaque with particular interest in their advantages and limitations as well as the clinical implications of the derived findings.
doi_str_mv 10.4330/wjc.v8.i9.520
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source Baishideng "World Journal of" online journals; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Atherosclerosis
Vulnerable
computed
coronary
magnetic
plaque
Diagnosis
Cardiac
resonance
Review
tomography
Cardiac
title Noninvasive diagnosis of vulnerable coronary plaque
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