Acanthamoeba castellanii Genotype T4 Stimulates the Production of Interleukin-10 as Well as Proinflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells, and Human Monocyte-Derived Macrophages

Free-living amoebae of the genus Acanthamoeba can cause severe and chronic infections in humans, mainly localized in immune privileged sites, such as the brain and the eye. Monocytes/macrophages are thought to be involved in Acanthamoeba infections, but little is known about how these facultative pa...

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Veröffentlicht in:	Infection and immunity 2016-10, Vol.84 (10), p.2953-2962
Hauptverfasser:	Mattana, Antonella, Sanna, Manuela, Cano, Antonella, Delogu, Giuseppe, Erre, Giuseppe, Roberts, Craig W, Henriquez, Fiona L, Fiori, Pier Luigi, Cappuccinelli, Piero
Format:	Artikel
Sprache:	eng
Schlagworte:	Acanthamoeba castellanii - immunology Amebiasis - immunology Analysis of Variance Cells, Cultured Cytokines - metabolism Enzyme-Linked Immunosorbent Assay Fungal and Parasitic Infections Genotype Humans Interleukin-10 - metabolism Leukocytes, Mononuclear - metabolism Macrophages - metabolism
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