Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes

Affordable next-generation sequencing (NGS) technologies for hepatitis C virus (HCV) may potentially identify both viral genotype and resistance genetic motifs in the era of directly acting antiviral (DAA) therapies. This study compared the ability of high-throughput NGS methods to generate full-len...

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Veröffentlicht in:	Journal of clinical microbiology 2016-10, Vol.54 (10), p.2470-2484
Hauptverfasser:	Thomson, Emma, Ip, Camilla L C, Badhan, Anjna, Christiansen, Mette T, Adamson, Walt, Ansari, M Azim, Bibby, David, Breuer, Judith, Brown, Anthony, Bowden, Rory, Bryant, Josie, Bonsall, David, Da Silva Filipe, Ana, Hinds, Chris, Hudson, Emma, Klenerman, Paul, Lythgow, Kieren, Mbisa, Jean L, McLauchlan, John, Myers, Richard, Piazza, Paolo, Roy, Sunando, Trebes, Amy, Sreenu, Vattipally B, Witteveldt, Jeroen, Barnes, Eleanor, Simmonds, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Resistance, Viral Genome, Viral Genotype Hepacivirus - classification Hepacivirus - genetics Hepatitis C - diagnosis Hepatitis C - virology Hepatitis C virus High-Throughput Nucleotide Sequencing - methods Humans Sequence Analysis, DNA - methods United Kingdom Virology
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