Cyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway

Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated the effect of COX-2 on β1-integrin expression and cell invasion in NSCLC. COX-2 and β1-integrin were co-expressed in NSCLC tissues. C...

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Veröffentlicht in:Scientific reports 2016-09, Vol.6 (1), p.33823-33823, Article 33823
Hauptverfasser: Pan, Jinshun, Yang, Qinyi, Shao, Jiaofang, Zhang, Li, Ma, Juan, Wang, Yipin, Jiang, Bing-Hua, Leng, Jing, Bai, Xiaoming
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Sprache:eng
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