Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations

Intrahepatic cholangiocarcinoma (ICC) is a biliary tree-origin epithelial malignancy in liver with unfavorable clinical outcomes. Systematic genome analyses may advance our understanding of ICC pathogenesis also improving current diagnostic and therapeutic modalities. In this study, we analyzed 17 I...

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Veröffentlicht in:	Oncotarget 2016-04, Vol.7 (17), p.23825-23836
Hauptverfasser:	Kim, Young-Ho, Hong, Eun-Kyung, Kong, Sun-Young, Han, Sung-Sik, Kim, Seoung-Hoon, Rhee, Je-Keun, Hwang, Soo-Kyung, Park, Sang-Jae, Kim, Tae-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bile Duct Neoplasms - classification Bile Duct Neoplasms - genetics Bile Duct Neoplasms - pathology Biomarkers, Tumor - genetics Cholangiocarcinoma - classification Cholangiocarcinoma - genetics Cholangiocarcinoma - pathology DNA Copy Number Variations Female Humans Male Middle Aged Mutation Prognosis Research Paper Survival Rate
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