Hodgkin's disease in a patient with common variable immunodeficiency
A 61 year old man with long standing common variable immunodeficiency presented with pyrexia, anaemia and leucopenia. A diagnoses of Hodgkin's disease of the bone marrow was made. The typical histopathological and immunophenotypic appearances were clearly distinct from those of T cell lymphoma...
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Veröffentlicht in: | Journal of clinical pathology 1995-09, Vol.48 (9), p.871-873 |
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creator | Christopoulos, C Papadaki, T Vlavianos, P Kokkini, G |
description | A 61 year old man with long standing common variable immunodeficiency presented with pyrexia, anaemia and leucopenia. A diagnoses of Hodgkin's disease of the bone marrow was made. The typical histopathological and immunophenotypic appearances were clearly distinct from those of T cell lymphoma with Reed-Sternberg-like cells which, in contrast to Hodgkin's disease, is a known complication of common variable immunodeficiency. Complete clinical and histological remission was achieved with combination chemotherapy. The latter was complicated by severe myelosuppression, unusually severe erosive mucositis and viral retinitis. |
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A diagnoses of Hodgkin's disease of the bone marrow was made. The typical histopathological and immunophenotypic appearances were clearly distinct from those of T cell lymphoma with Reed-Sternberg-like cells which, in contrast to Hodgkin's disease, is a known complication of common variable immunodeficiency. Complete clinical and histological remission was achieved with combination chemotherapy. The latter was complicated by severe myelosuppression, unusually severe erosive mucositis and viral retinitis.</description><identifier>ISSN: 0021-9746</identifier><identifier>EISSN: 1472-4146</identifier><identifier>DOI: 10.1136/jcp.48.9.871</identifier><identifier>PMID: 7490326</identifier><identifier>CODEN: JCPAAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Association of Clinical Pathologists</publisher><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Biological and medical sciences ; Common Variable Immunodeficiency - complications ; Hematologic and hematopoietic diseases ; Hodgkin Disease - drug therapy ; Hodgkin Disease - etiology ; Hodgkin Disease - pathology ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Male ; Medical sciences ; Middle Aged</subject><ispartof>Journal of clinical pathology, 1995-09, Vol.48 (9), p.871-873</ispartof><rights>1995 INIST-CNRS</rights><rights>Copyright BMJ Publishing Group LTD Sep 1995</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b505t-eb50608745eec0408994210b3f9e2f4f9cb05e2aaf878eeeb48620ca01f7875f3</citedby><cites>FETCH-LOGICAL-b505t-eb50608745eec0408994210b3f9e2f4f9cb05e2aaf878eeeb48620ca01f7875f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC502881/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC502881/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3677065$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7490326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christopoulos, C</creatorcontrib><creatorcontrib>Papadaki, T</creatorcontrib><creatorcontrib>Vlavianos, P</creatorcontrib><creatorcontrib>Kokkini, G</creatorcontrib><title>Hodgkin's disease in a patient with common variable immunodeficiency</title><title>Journal of clinical pathology</title><addtitle>J Clin Pathol</addtitle><description>A 61 year old man with long standing common variable immunodeficiency presented with pyrexia, anaemia and leucopenia. A diagnoses of Hodgkin's disease of the bone marrow was made. The typical histopathological and immunophenotypic appearances were clearly distinct from those of T cell lymphoma with Reed-Sternberg-like cells which, in contrast to Hodgkin's disease, is a known complication of common variable immunodeficiency. Complete clinical and histological remission was achieved with combination chemotherapy. The latter was complicated by severe myelosuppression, unusually severe erosive mucositis and viral retinitis.</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Common Variable Immunodeficiency - complications</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hodgkin Disease - drug therapy</subject><subject>Hodgkin Disease - etiology</subject><subject>Hodgkin Disease - pathology</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><issn>0021-9746</issn><issn>1472-4146</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kc9PFDEYhhujwQW9eTWZRCMXZ207_TUHDmZBIBA1Rrk2ne5X6DLTru0Myn9PyW426sHTd3ifr32-vAi9InhOSCM-rOx6ztS8nStJnqAZYZLWjDDxFM0wpqRuJRPP0X7OK4xJI0mzh_Yka3FDxQwdn8Xl9a0Ph7la-gwmQ-VDZaq1GT2Esfrlx5vKxmGIobozyZuuL8QwTCEuwXlbIHv_Aj1zps_wcjsP0I9PJ98XZ_Xll9PzxcfLuuOYjzWUIbCSjANYzLBqW0YJ7hrXAnXMtbbDHKgxTkkFAB1TgmJrMHFSSe6aA3S0eXc9dQMsbRFMptfr5AeT7nU0Xv-dBH-jr-Od5pgqRcr-u-1-ij8nyKMefLbQ9yZAnLKWUjIpKC_gm3_AVZxSKLdpIiVmnAuqCvV-Q9kUc07gdiYE68dqdKlGM6VbXaop-Os_7XfwtouSv93mJlvTu2SC9XmHNaL8LB7d6g3m8wi_d7FJt1rIRnL9-Wqh2cXVt-aUEv218IcbvhtW_xd8ACzIsqs</recordid><startdate>19950901</startdate><enddate>19950901</enddate><creator>Christopoulos, C</creator><creator>Papadaki, T</creator><creator>Vlavianos, P</creator><creator>Kokkini, G</creator><general>BMJ Publishing Group Ltd and Association of Clinical Pathologists</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19950901</creationdate><title>Hodgkin's disease in a patient with common variable immunodeficiency</title><author>Christopoulos, C ; Papadaki, T ; Vlavianos, P ; Kokkini, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b505t-eb50608745eec0408994210b3f9e2f4f9cb05e2aaf878eeeb48620ca01f7875f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Common Variable Immunodeficiency - complications</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hodgkin Disease - drug therapy</topic><topic>Hodgkin Disease - etiology</topic><topic>Hodgkin Disease - pathology</topic><topic>Humans</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christopoulos, C</creatorcontrib><creatorcontrib>Papadaki, T</creatorcontrib><creatorcontrib>Vlavianos, P</creatorcontrib><creatorcontrib>Kokkini, G</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christopoulos, C</au><au>Papadaki, T</au><au>Vlavianos, P</au><au>Kokkini, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hodgkin's disease in a patient with common variable immunodeficiency</atitle><jtitle>Journal of clinical pathology</jtitle><addtitle>J Clin Pathol</addtitle><date>1995-09-01</date><risdate>1995</risdate><volume>48</volume><issue>9</issue><spage>871</spage><epage>873</epage><pages>871-873</pages><issn>0021-9746</issn><eissn>1472-4146</eissn><coden>JCPAAK</coden><abstract>A 61 year old man with long standing common variable immunodeficiency presented with pyrexia, anaemia and leucopenia. A diagnoses of Hodgkin's disease of the bone marrow was made. The typical histopathological and immunophenotypic appearances were clearly distinct from those of T cell lymphoma with Reed-Sternberg-like cells which, in contrast to Hodgkin's disease, is a known complication of common variable immunodeficiency. Complete clinical and histological remission was achieved with combination chemotherapy. The latter was complicated by severe myelosuppression, unusually severe erosive mucositis and viral retinitis.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Association of Clinical Pathologists</pub><pmid>7490326</pmid><doi>10.1136/jcp.48.9.871</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Common Variable Immunodeficiency - complications Hematologic and hematopoietic diseases Hodgkin Disease - drug therapy Hodgkin Disease - etiology Hodgkin Disease - pathology Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged |
title | Hodgkin's disease in a patient with common variable immunodeficiency |
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