PABP enhances release factor recruitment and stop codon recognition during translation termination

Poly(A)-binding protein (PABP) is a major component of the messenger RNA-protein complex. PABP is able to bind the poly(A) tail of mRNA, as well as translation initiation factor 4G and eukaryotic release factor 3a (eRF3a). PABP has been found to stimulate translation initiation and to inhibit nonsen...

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Veröffentlicht in:	Nucleic acids research 2016-09, Vol.44 (16), p.7766-7776
Hauptverfasser:	Ivanov, Alexandr, Mikhailova, Tatyana, Eliseev, Boris, Yeramala, Lahari, Sokolova, Elizaveta, Susorov, Denis, Shuvalov, Alexey, Schaffitzel, Christiane, Alkalaeva, Elena
Format:	Artikel
Sprache:	eng
Schlagworte:	Codon, Terminator - metabolism Humans Hydrolysis Models, Biological Molecular Biology Peptide Chain Termination, Translational - genetics Peptide Termination Factors - metabolism Poly(A)-Binding Proteins - metabolism Protein Binding RNA, Transfer, Amino Acyl
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