Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study)
The association between the J-wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J-wave. We examined the association between the J-wave, detected by an automated m...
Gespeichert in:
| Veröffentlicht in: | The American journal of cardiology 2016-09, Vol.118 (6), p.811-815 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 815 |
|---|---|
| container_issue | 6 |
| container_start_page | 811 |
| container_title | The American journal of cardiology |
| container_volume | 118 |
| creator | O'Neal, Wesley T., MD, MPH Wang, Yi (Grace), PhD Wu, Hau-Tieng, MD, PhD Zhang, Zhu-Ming, MD, MPH Li, Yabing, MD Tereshchenko, Larisa G., MD, PhD Estes, E. Harvey, MD Daubechies, Ingrid, PhD Soliman, Elsayed Z., MD, MSc, MS |
| description | The association between the J-wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J-wave. We examined the association between the J-wave, detected by an automated method, and adverse cardiovascular outcomes in 14,592 (mean age = 54 ± 5.8 years; 56% female; 26% black) participants from the Atherosclerosis Risk In Communities (ARIC) study. The J-wave was detected at baseline (1987-1989) and during follow-up study visits (1990-1992, 1993-1995, and 1996-1998) using a fully automated method. Sudden cardiac death (SCD), coronary heart disease (CHD) death, and cardiovascular mortality were ascertained from hospital discharge records, death certificates, and autopsy data through December 31, 2010. A total of 278 (1.9%) participants had evidence of a J-wave. Over a median follow-up of 22 years, 4,376 (30%) of the participants died. In a multivariable Cox regression analysis adjusted for demographics, cardiovascular risk factors, and potential confounders, the J-wave was not associated with an increased risk of SCD (HR = 0.74, 95%CI = 0.36, 1.50), CHD death (HR = 0.72, 95%CI = 0.40, 1.32), or cardiovascular mortality (HR = 1.16, 95%CI = 0.87, 1.56). An interaction was detected for cardiovascular mortality by sex with males (HR = 1.54, 95%CI = 1.09, 2.19) having a stronger association than females (HR = 0.74, 95%CI = 0.43, 1.25) (P-interaction = 0.030). In conclusion, our findings suggest that the J-wave is a benign entity that is not associated with an increased risk for sudden cardiac arrest among middle aged adults in the United States. |
| doi_str_mv | 10.1016/j.amjcard.2016.06.047 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5021615</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002914916311183</els_id><sourcerecordid>1819432252</sourcerecordid><originalsourceid>FETCH-LOGICAL-c649t-8acda19c3e7ffca05d7ce2219abd505002e93c430725c493b32f5e4bf551e5ba3</originalsourceid><addsrcrecordid>eNqFUsFu1DAQjRCILoVPAEXiUg5ZPHacxJdW1aotoEpFFMTRcpxJ19vEXuxkpf0BvrtOdynQSyVrrNF78zwzfknyFsgcCBQfV3PVr7TyzZzGdE7iyctnyQyqUmQggD1PZoQQmgnIxUHyKoRVTAF48TI5oCUXBaPFLPl91qEevJuUjLvxar00Ov2S_VQbTJVt0sU9sFFBj53y6dU4aNdjSI1NhyWmF2jRqy796tYRH4yz6VHrXX8PnsbgXdDdFE1Iv5lwOxUuXN-P1gwm6lwPY7P98Dp50aou4Jv9fZj8OD_7vviUXV5dfF6cXma6yMWQVUo3CoRmWLatVoQ3pUZKQai64YTHcVEwnTNSUq5zwWpGW4553XIOyGvFDpPjne56rHtsNNohdi_X3vTKb6VTRv6PWLOUN24jOaFQAI8CR3sB736NGAbZm6Cx65RFNwYJFS0rIVj8gKepIHJGKaeR-v4RdeVGb-MmJkEKnIqqiCy-Y-m4zuCxfegbiJxMIVdybwo5mUKSePIy1r37d-iHqj8uiISTHQHj6jcGvQzaoNXYGB_dIRtnnnzi-JGC7ow1WnW3uMXwdxoZqCTyenLmZEwoGABUjN0BCdLiOw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1822152986</pqid></control><display><type>article</type><title>Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study)</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>ProQuest Central UK/Ireland</source><creator>O'Neal, Wesley T., MD, MPH ; Wang, Yi (Grace), PhD ; Wu, Hau-Tieng, MD, PhD ; Zhang, Zhu-Ming, MD, MPH ; Li, Yabing, MD ; Tereshchenko, Larisa G., MD, PhD ; Estes, E. Harvey, MD ; Daubechies, Ingrid, PhD ; Soliman, Elsayed Z., MD, MSc, MS</creator><creatorcontrib>O'Neal, Wesley T., MD, MPH ; Wang, Yi (Grace), PhD ; Wu, Hau-Tieng, MD, PhD ; Zhang, Zhu-Ming, MD, MPH ; Li, Yabing, MD ; Tereshchenko, Larisa G., MD, PhD ; Estes, E. Harvey, MD ; Daubechies, Ingrid, PhD ; Soliman, Elsayed Z., MD, MSc, MS</creatorcontrib><description>The association between the J-wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J-wave. We examined the association between the J-wave, detected by an automated method, and adverse cardiovascular outcomes in 14,592 (mean age = 54 ± 5.8 years; 56% female; 26% black) participants from the Atherosclerosis Risk In Communities (ARIC) study. The J-wave was detected at baseline (1987-1989) and during follow-up study visits (1990-1992, 1993-1995, and 1996-1998) using a fully automated method. Sudden cardiac death (SCD), coronary heart disease (CHD) death, and cardiovascular mortality were ascertained from hospital discharge records, death certificates, and autopsy data through December 31, 2010. A total of 278 (1.9%) participants had evidence of a J-wave. Over a median follow-up of 22 years, 4,376 (30%) of the participants died. In a multivariable Cox regression analysis adjusted for demographics, cardiovascular risk factors, and potential confounders, the J-wave was not associated with an increased risk of SCD (HR = 0.74, 95%CI = 0.36, 1.50), CHD death (HR = 0.72, 95%CI = 0.40, 1.32), or cardiovascular mortality (HR = 1.16, 95%CI = 0.87, 1.56). An interaction was detected for cardiovascular mortality by sex with males (HR = 1.54, 95%CI = 1.09, 2.19) having a stronger association than females (HR = 0.74, 95%CI = 0.43, 1.25) (P-interaction = 0.030). In conclusion, our findings suggest that the J-wave is a benign entity that is not associated with an increased risk for sudden cardiac arrest among middle aged adults in the United States.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2016.06.047</identifier><identifier>PMID: 27596326</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>African Americans ; Brugada Syndrome - epidemiology ; Cardiac Conduction System Disease ; Cardiovascular ; Cardiovascular disease ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - mortality ; Cohort Studies ; Coronary Disease - epidemiology ; Coronary Disease - mortality ; Death, Sudden, Cardiac - epidemiology ; Electrocardiography ; European Continental Ancestry Group ; Female ; Follow-Up Studies ; Health risk assessment ; Humans ; Low density lipoprotein ; Male ; Middle Aged ; Multivariate Analysis ; Proportional Hazards Models ; Prospective Studies ; Risk Factors ; Sex Factors ; United States - epidemiology</subject><ispartof>The American journal of cardiology, 2016-09, Vol.118 (6), p.811-815</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Sep 15, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c649t-8acda19c3e7ffca05d7ce2219abd505002e93c430725c493b32f5e4bf551e5ba3</citedby><cites>FETCH-LOGICAL-c649t-8acda19c3e7ffca05d7ce2219abd505002e93c430725c493b32f5e4bf551e5ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1822152986?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27596326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Neal, Wesley T., MD, MPH</creatorcontrib><creatorcontrib>Wang, Yi (Grace), PhD</creatorcontrib><creatorcontrib>Wu, Hau-Tieng, MD, PhD</creatorcontrib><creatorcontrib>Zhang, Zhu-Ming, MD, MPH</creatorcontrib><creatorcontrib>Li, Yabing, MD</creatorcontrib><creatorcontrib>Tereshchenko, Larisa G., MD, PhD</creatorcontrib><creatorcontrib>Estes, E. Harvey, MD</creatorcontrib><creatorcontrib>Daubechies, Ingrid, PhD</creatorcontrib><creatorcontrib>Soliman, Elsayed Z., MD, MSc, MS</creatorcontrib><title>Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study)</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>The association between the J-wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J-wave. We examined the association between the J-wave, detected by an automated method, and adverse cardiovascular outcomes in 14,592 (mean age = 54 ± 5.8 years; 56% female; 26% black) participants from the Atherosclerosis Risk In Communities (ARIC) study. The J-wave was detected at baseline (1987-1989) and during follow-up study visits (1990-1992, 1993-1995, and 1996-1998) using a fully automated method. Sudden cardiac death (SCD), coronary heart disease (CHD) death, and cardiovascular mortality were ascertained from hospital discharge records, death certificates, and autopsy data through December 31, 2010. A total of 278 (1.9%) participants had evidence of a J-wave. Over a median follow-up of 22 years, 4,376 (30%) of the participants died. In a multivariable Cox regression analysis adjusted for demographics, cardiovascular risk factors, and potential confounders, the J-wave was not associated with an increased risk of SCD (HR = 0.74, 95%CI = 0.36, 1.50), CHD death (HR = 0.72, 95%CI = 0.40, 1.32), or cardiovascular mortality (HR = 1.16, 95%CI = 0.87, 1.56). An interaction was detected for cardiovascular mortality by sex with males (HR = 1.54, 95%CI = 1.09, 2.19) having a stronger association than females (HR = 0.74, 95%CI = 0.43, 1.25) (P-interaction = 0.030). In conclusion, our findings suggest that the J-wave is a benign entity that is not associated with an increased risk for sudden cardiac arrest among middle aged adults in the United States.</description><subject>African Americans</subject><subject>Brugada Syndrome - epidemiology</subject><subject>Cardiac Conduction System Disease</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - mortality</subject><subject>Cohort Studies</subject><subject>Coronary Disease - epidemiology</subject><subject>Coronary Disease - mortality</subject><subject>Death, Sudden, Cardiac - epidemiology</subject><subject>Electrocardiography</subject><subject>European Continental Ancestry Group</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Low density lipoprotein</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Proportional Hazards Models</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>United States - epidemiology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFUsFu1DAQjRCILoVPAEXiUg5ZPHacxJdW1aotoEpFFMTRcpxJ19vEXuxkpf0BvrtOdynQSyVrrNF78zwzfknyFsgcCBQfV3PVr7TyzZzGdE7iyctnyQyqUmQggD1PZoQQmgnIxUHyKoRVTAF48TI5oCUXBaPFLPl91qEevJuUjLvxar00Ov2S_VQbTJVt0sU9sFFBj53y6dU4aNdjSI1NhyWmF2jRqy796tYRH4yz6VHrXX8PnsbgXdDdFE1Iv5lwOxUuXN-P1gwm6lwPY7P98Dp50aou4Jv9fZj8OD_7vviUXV5dfF6cXma6yMWQVUo3CoRmWLatVoQ3pUZKQai64YTHcVEwnTNSUq5zwWpGW4553XIOyGvFDpPjne56rHtsNNohdi_X3vTKb6VTRv6PWLOUN24jOaFQAI8CR3sB736NGAbZm6Cx65RFNwYJFS0rIVj8gKepIHJGKaeR-v4RdeVGb-MmJkEKnIqqiCy-Y-m4zuCxfegbiJxMIVdybwo5mUKSePIy1r37d-iHqj8uiISTHQHj6jcGvQzaoNXYGB_dIRtnnnzi-JGC7ow1WnW3uMXwdxoZqCTyenLmZEwoGABUjN0BCdLiOw</recordid><startdate>20160915</startdate><enddate>20160915</enddate><creator>O'Neal, Wesley T., MD, MPH</creator><creator>Wang, Yi (Grace), PhD</creator><creator>Wu, Hau-Tieng, MD, PhD</creator><creator>Zhang, Zhu-Ming, MD, MPH</creator><creator>Li, Yabing, MD</creator><creator>Tereshchenko, Larisa G., MD, PhD</creator><creator>Estes, E. Harvey, MD</creator><creator>Daubechies, Ingrid, PhD</creator><creator>Soliman, Elsayed Z., MD, MSc, MS</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QO</scope><scope>5PM</scope></search><sort><creationdate>20160915</creationdate><title>Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study)</title><author>O'Neal, Wesley T., MD, MPH ; Wang, Yi (Grace), PhD ; Wu, Hau-Tieng, MD, PhD ; Zhang, Zhu-Ming, MD, MPH ; Li, Yabing, MD ; Tereshchenko, Larisa G., MD, PhD ; Estes, E. Harvey, MD ; Daubechies, Ingrid, PhD ; Soliman, Elsayed Z., MD, MSc, MS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c649t-8acda19c3e7ffca05d7ce2219abd505002e93c430725c493b32f5e4bf551e5ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>African Americans</topic><topic>Brugada Syndrome - epidemiology</topic><topic>Cardiac Conduction System Disease</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - mortality</topic><topic>Cohort Studies</topic><topic>Coronary Disease - epidemiology</topic><topic>Coronary Disease - mortality</topic><topic>Death, Sudden, Cardiac - epidemiology</topic><topic>Electrocardiography</topic><topic>European Continental Ancestry Group</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Low density lipoprotein</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Proportional Hazards Models</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Neal, Wesley T., MD, MPH</creatorcontrib><creatorcontrib>Wang, Yi (Grace), PhD</creatorcontrib><creatorcontrib>Wu, Hau-Tieng, MD, PhD</creatorcontrib><creatorcontrib>Zhang, Zhu-Ming, MD, MPH</creatorcontrib><creatorcontrib>Li, Yabing, MD</creatorcontrib><creatorcontrib>Tereshchenko, Larisa G., MD, PhD</creatorcontrib><creatorcontrib>Estes, E. Harvey, MD</creatorcontrib><creatorcontrib>Daubechies, Ingrid, PhD</creatorcontrib><creatorcontrib>Soliman, Elsayed Z., MD, MSc, MS</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Neal, Wesley T., MD, MPH</au><au>Wang, Yi (Grace), PhD</au><au>Wu, Hau-Tieng, MD, PhD</au><au>Zhang, Zhu-Ming, MD, MPH</au><au>Li, Yabing, MD</au><au>Tereshchenko, Larisa G., MD, PhD</au><au>Estes, E. Harvey, MD</au><au>Daubechies, Ingrid, PhD</au><au>Soliman, Elsayed Z., MD, MSc, MS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study)</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2016-09-15</date><risdate>2016</risdate><volume>118</volume><issue>6</issue><spage>811</spage><epage>815</epage><pages>811-815</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The association between the J-wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J-wave. We examined the association between the J-wave, detected by an automated method, and adverse cardiovascular outcomes in 14,592 (mean age = 54 ± 5.8 years; 56% female; 26% black) participants from the Atherosclerosis Risk In Communities (ARIC) study. The J-wave was detected at baseline (1987-1989) and during follow-up study visits (1990-1992, 1993-1995, and 1996-1998) using a fully automated method. Sudden cardiac death (SCD), coronary heart disease (CHD) death, and cardiovascular mortality were ascertained from hospital discharge records, death certificates, and autopsy data through December 31, 2010. A total of 278 (1.9%) participants had evidence of a J-wave. Over a median follow-up of 22 years, 4,376 (30%) of the participants died. In a multivariable Cox regression analysis adjusted for demographics, cardiovascular risk factors, and potential confounders, the J-wave was not associated with an increased risk of SCD (HR = 0.74, 95%CI = 0.36, 1.50), CHD death (HR = 0.72, 95%CI = 0.40, 1.32), or cardiovascular mortality (HR = 1.16, 95%CI = 0.87, 1.56). An interaction was detected for cardiovascular mortality by sex with males (HR = 1.54, 95%CI = 1.09, 2.19) having a stronger association than females (HR = 0.74, 95%CI = 0.43, 1.25) (P-interaction = 0.030). In conclusion, our findings suggest that the J-wave is a benign entity that is not associated with an increased risk for sudden cardiac arrest among middle aged adults in the United States.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27596326</pmid><doi>10.1016/j.amjcard.2016.06.047</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 2016-09, Vol.118 (6), p.811-815 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5021615 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | African Americans Brugada Syndrome - epidemiology Cardiac Conduction System Disease Cardiovascular Cardiovascular disease Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Cohort Studies Coronary Disease - epidemiology Coronary Disease - mortality Death, Sudden, Cardiac - epidemiology Electrocardiography European Continental Ancestry Group Female Follow-Up Studies Health risk assessment Humans Low density lipoprotein Male Middle Aged Multivariate Analysis Proportional Hazards Models Prospective Studies Risk Factors Sex Factors United States - epidemiology |
| title | Electrocardiographic J-Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk in Communities Study) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T18%3A46%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Electrocardiographic%20J-Wave%20and%20Cardiovascular%20Outcomes%20in%20the%20General%20Population%20(from%20the%20Atherosclerosis%20Risk%20in%20Communities%20Study)&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=O'Neal,%20Wesley%20T.,%20MD,%20MPH&rft.date=2016-09-15&rft.volume=118&rft.issue=6&rft.spage=811&rft.epage=815&rft.pages=811-815&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2016.06.047&rft_dat=%3Cproquest_pubme%3E1819432252%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1822152986&rft_id=info:pmid/27596326&rft_els_id=1_s2_0_S0002914916311183&rfr_iscdi=true |