Antibody for detecting p53 protein by immunohistochemistry in normal tissues

AIMS--To establish whether PAb248 recognises human p53 as well as murine p53 and if so, to determine its distribution in normal tissues. METHODS--The ability of PAb248 to recognise human p53 was established by analysis of the human osteosarcoma derived Saos-2 cell line, which lacks the p53 gene, bef...

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Veröffentlicht in:	Journal of clinical pathology 1994-07, Vol.47 (7), p.592-596
Hauptverfasser:	Pezzella, F, Micklem, K, Turley, H, Pulford, K, Jones, M, Kocialkowski, S, Delia, D, Aiello, A, Bicknell, R, Smith, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Biological and medical sciences Blotting, Western Humans Immunoenzyme Techniques Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous. Technology Osteosarcoma - chemistry Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Precipitin Tests Transfection Tumor Cells, Cultured Tumor Suppressor Protein p53 - analysis Tumor Suppressor Protein p53 - genetics
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