Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans
Our ability to understand speech requires neural tuning with high frequency resolution, but the peripheral mechanisms underlying sharp tuning in humans remain unclear. Sharp tuning in genetically modified mice has been attributed to decreases in spread of excitation of tectorial membrane traveling w...
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| Veröffentlicht in: | Biophysical journal 2016-09, Vol.111 (5), p.921-924 |
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| container_title | Biophysical journal |
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| creator | Farrahi, Shirin Ghaffari, Roozbeh Sellon, Jonathan B. Nakajima, Hideko H. Freeman, Dennis M. |
| description | Our ability to understand speech requires neural tuning with high frequency resolution, but the peripheral mechanisms underlying sharp tuning in humans remain unclear. Sharp tuning in genetically modified mice has been attributed to decreases in spread of excitation of tectorial membrane traveling waves. Here we show that the spread of excitation of tectorial membrane waves is similar in humans and mice, although the mechanical excitation spans fewer frequencies in humans—suggesting a possible mechanism for sharper tuning. |
| doi_str_mv | 10.1016/j.bpj.2016.07.038 |
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| source | MEDLINE; Cell Press Free Archives; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ScienceDirect Journals (5 years ago - present); PubMed Central |
| subjects | Animals Biomechanical Phenomena Biophysical Letter Biophysics Hearing - physiology Humans In Vitro Techniques Membranes Mice Motion Physical Stimulation Rodents Sound Species Specificity Speech Perception - physiology Tectorial Membrane - physiology Viscosity |
| title | Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans |
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