Mass concentration in a nonlocal model of clonal selection

Self-renewal is a constitutive property of stem cells. Testing the cancer stem cell hypothesis requires investigation of the impact of self-renewal on cancer expansion. To better understand this impact, we propose a mathematical model describing the dynamics of a continuum of cell clones structured...

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Veröffentlicht in:	Journal of mathematical biology 2016-10, Vol.73 (4), p.1001-1033
Hauptverfasser:	Busse, J.-E., Gwiazda, P., Marciniak-Czochra, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Applications of Mathematics Cell Differentiation Cell Proliferation Clone Cells Computer Simulation Humans Mathematical and Computational Biology Mathematics Mathematics and Statistics Models, Biological Neoplasms Stem Cells
Online-Zugang:	Volltext
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