Extract of Ganoderma formosanum Mycelium as a Highly Potent Tyrosinase Inhibitor

In this study, the inhibitory effect of Ganoderma formosanum mycelium extracts on tyrosinase, the central regulatory enzyme being responsible for cutaneous pigmentation, was investigated in both cell-free and cellular enzymatic systems, as well as in phenotype-based zebrafish model. Bioassay-guided...

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Veröffentlicht in:	Scientific reports 2016-09, Vol.6 (1), p.32854, Article 32854
Hauptverfasser:	Hsu, Kai-Di, Chen, Hong-Jhang, Wang, Chi-Shin, Lum, Chi-Chin, Wu, Shu-Pei, Lin, Shin-Ping, Cheng, Kuan-Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/2234 631/326/2522 64/116 82/1 82/29 Acetic acid Biosynthesis Cosmetics Cytotoxicity Drug dosages Enzymes Ethyl acetate Fruit bodies Genotype & phenotype Humanities and Social Sciences Kojic acid Melanin Melanoma multidisciplinary Pigmentation Proteins Science Skin Standard deviation Toxicity Zebrafish
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