Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients

AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve Egyptian patients infected with hepatitis C virus(HCV) genotype 4.METHODS This study included 180 subjects,composed of 120 treatment-na?ve chronic...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2016-09, Vol.22 (34), p.7767-7777
Hauptverfasser:	Bader El Din, Noha G, Farouk, Sally, El-Shenawy, Reem, Ibrahim, Marwa K, Dawood, Reham M, Elhady, Mostafa M, Salem, Ahmed M, Zayed, Naglaa, Khairy, Ahmed, El Awady, Mostafa K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged alpha Single Basic Study Case-Control Studies disease Egypt Enzyme-Linked Immunosorbent Assay expression Liver factor Female Hepacivirus - genetics Hepatitis Hepatitis C - complications Hepatitis C - pathology Humans immune Inflammation Liver - pathology Liver Cirrhosis - pathology Male Middle Aged necrosis nucleotide Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide polymorphisms Cytokine progression response Tumor Tumor Necrosis Factor-alpha - blood Tumor Necrosis Factor-alpha - genetics virus
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