Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study

Summary Background Chronic injury in kidney transplants remains a major cause of allograft loss. The aim of this study was to identify a gene set capable of predicting renal allografts at risk of progressive injury due to fibrosis. Methods This Genomics of Chronic Allograft Rejection (GoCAR) study i...

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Veröffentlicht in:	The Lancet (British edition) 2016-09, Vol.388 (10048), p.983-993
Hauptverfasser:	O'Connell, Philip J, MD, Zhang, Weijia, PhD, Menon, Madhav C, MD, Yi, Zhengzi, MS, Schröppel, Bernd, MD, Gallon, Lorenzo, MD, Luan, Yi, PhD, Rosales, Ivy A, MD, Ge, Yongchao, PhD, Losic, Bojan, PhD, Xi, Caixia, MS, Woytovich, Christopher, BS, Keung, Karen L, MD, Wei, Chengguo, PhD, Greene, Ilana, MS, Overbey, Jessica, MS, Bagiella, Emilia, PhD, Najafian, Nader, MD, Samaniego, Milagros, MD, Djamali, Arjang, MD, Alexander, Stephen I, MD, Nankivell, Brian J, MD, Chapman, Jeremy R, MD, Smith, Rex Neal, MD, Colvin, Robert, MD, Murphy, Barbara, Dr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antigens Biopsy Fibrosis - genetics Fibrosis - prevention & control Gene expression Gene Expression Profiling - methods Genetic Testing Graft Rejection - genetics Graft Rejection - prevention & control Health risk assessment Humans Internal Medicine Kidney - pathology Kidney transplantation Kidney Transplantation - adverse effects Kidneys Male Middle Aged Prospective Studies Renal function Renal Insufficiency, Chronic - genetics Transplants & implants Young Adult
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