The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH)

Visceral obesity and metabolic syndrome are commonly associated with non-alcoholic fatty liver disease (NAFLD). The progression of steatosis to NASH depends on a number of metabolic and patient-related factors. The mechanisms of genetic predisposition towards the development of NASH and related fibr...

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Veröffentlicht in:	BMC medical genetics 2016-09, Vol.17 (1), p.63-63, Article 63
Hauptverfasser:	Mehta, Rohini, Jeiran, Kianoush, Koenig, Aaron B, Otgonsuren, Munkzhul, Goodman, Zachary, Baranova, Ancha, Younossi, Zobair
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Biopsy Body mass index Complications and side effects Fatty liver Female Genetic Predisposition to Disease Genetic testing Genome, Mitochondrial Genomics Genomics - methods Haplotypes Humans Hypotheses Inflammation Lipase - genetics Liver - pathology Liver cancer Liver diseases Male Membrane Proteins - genetics Metabolic syndrome Metabolic syndrome X Metabolites Middle Aged Mitochondria - genetics Mutation Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - pathology Obesity Patients Polymorphism, Single Nucleotide Proteins Sequence Analysis, DNA - methods Thermal cycling Triglycerides
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