Validation of a Novel Biomarker Panel for the Detection of Ovarian Cancer

Ovarian cancer is the most lethal gynecological malignancy. Our integrated -omics approach to ovarian cancer biomarker discovery has identified kallikrein 6 (KLK6) and folate-receptor 1 (FOLR1) as promising candidates but these markers require further validation. KLK6, FOLR1, CA125, and HE4 were inv...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2016-09, Vol.25 (9), p.1333-1340
Hauptverfasser:	Leung, Felix, Bernardini, Marcus Q, Brown, Marshall D, Zheng, Yingye, Molina, Rafael, Bast, Jr, Robert C, Davis, Gerard, Serra, Stefano, Diamandis, Eleftherios P, Kulasingam, Vathany
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - blood CA-125 Antigen - blood Case-Control Studies Early Detection of Cancer - methods Enzyme-Linked Immunosorbent Assay Female Folate Receptor 1 - blood Humans Kallikreins - blood Middle Aged Ovarian Neoplasms - blood Ovarian Neoplasms - diagnosis Ovarian Neoplasms - pathology Proteins - analysis Retrospective Studies ROC Curve Sensitivity and Specificity
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