A Novel and Multivalent Role of Pax6 in Cerebellar Development

Pax6 is a prominent gene in brain development. The deletion of Pax6 results in devastated development of eye, olfactory bulb, and cortex. However, it has been reported that the Pax6-null Sey cerebellum only has minor defects involving granule cells despite Pax6 being expressed throughout cerebellar...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2016-08, Vol.36 (35), p.9057-9069
Hauptverfasser:	Yeung, Joanna, Ha, Thomas J, Swanson, Douglas J, Goldowitz, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Bromodeoxyuridine - metabolism Caspase 3 - metabolism Cell Count Cerebellum - cytology Cerebellum - embryology Cerebellum - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Embryo, Mammalian Gene Expression Regulation, Developmental - genetics Glutamic Acid - metabolism LIM-Homeodomain Proteins - genetics LIM-Homeodomain Proteins - metabolism Luminescent Proteins - genetics Luminescent Proteins - metabolism Mice Mice, Mutant Strains Microscopy, Confocal PAX6 Transcription Factor - genetics PAX6 Transcription Factor - metabolism Transcription Factors - genetics Transcription Factors - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!