Adolescents with classical polycystic ovary syndrome have alterations in the surrogate markers of cardiovascular disease but not in the endothelial function. The possible benefits of metformin

Abstract Study Objective To study whether adolescents with the classical form of polycystic ovary syndrome have alterations in metabolic and vascular structure and function. The effect of metformin was evaluated. Design Controlled study Setting University outpatient clinic Participants Eighteen PCOS...

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Veröffentlicht in:	Journal of pediatric & adolescent gynecology 2016-10, Vol.29 (5), p.489-495
Hauptverfasser:	Fruzzetti, F., MD, Ghiadoni, L., MD, Virdis, A., MD, De Negri, F., MD, Perini, D., MD, Bucci, F., MD, Giannarelli, C., MD, Gadducci, A., MD, Taddei, S., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Arterial stiffness Biomarkers - blood Blood Glucose - drug effects C-Reactive Protein - metabolism Cardiovascular Diseases - blood Cardiovascular Diseases - drug therapy Carotid Intima-Media Thickness Case-Control Studies Endothelium Female Fibrinolysis Homocysteine - blood Humans Hypoglycemic Agents - therapeutic use Insulin - blood Insulin Resistance Lipids - blood Metformin Metformin - therapeutic use Obstetrics and Gynecology PCOS Pediatrics Plasminogen Activator Inhibitor 1 - blood Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - drug therapy Pulse Wave Analysis Risk Factors Tissue Plasminogen Activator - blood
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