Assembly scaffold NifEN: A structural and functional homolog of the nitrogenase catalytic component

NifEN is a biosynthetic scaffold for the cofactor of Mo-nitrogenase (designated the M-cluster). Previous studies have revealed the sequence and structural homology between NifEN and NifDK, the catalytic component of nitrogenase. However, direct proof for the functional homology between the two prote...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-08, Vol.113 (34), p.9504-9508
Hauptverfasser:	Fay, Aaron W., Blank, Michael A., Rebelein, Johannes G., Lee, Chi Chung, Ribbe, Markus W., Hedman, Britt, Hodgson, Keith O., Hu, Yilin
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption spectroscopy Adenosine triphosphatase Azotobacter vinelandii - chemistry Azotobacter vinelandii - enzymology Binding sites Biological Sciences Catalytic Domain Chelation Coenzymes - chemistry Coenzymes - isolation & purification Coenzymes - metabolism Iron Iron - chemistry Iron - metabolism Iron Chelating Agents - chemistry Molybdenum - chemistry Molybdenum - metabolism Molybdoferredoxin - chemistry Molybdoferredoxin - isolation & purification Molybdoferredoxin - metabolism Nitrogenase - chemistry Nitrogenase - metabolism Oxidoreductases - chemistry Oxidoreductases - metabolism Protein Binding Protein Multimerization Protein Subunits - chemistry Protein Subunits - metabolism Proteins Relocation Substrates
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